Discussions By Condition: Liver conditions

Unexplained Hepatomegaly - GI symptoms... Hormonal birth control?

Posted In: Liver conditions 0 Replies
  • Posted By: Anonymous
  • September 21, 2018
  • 06:06 PM

I am an otherwise health, 32 y.o. white female. In June 2018 I began experiencing "episodes" of extreme GI distress. I've been recording them because there is now too much to remember:

6/4/18: nausea, vomiting, fever, chills, extreme bloating, severe abdominal pain
6/19/18: nausea, vomiting, diarrhea, fever, bloating, abdominal pain
7/5/18: nausea, vomiting, diarrhea, bloating, abdominal pain
7/27/18: nausea, vomiting, diarrhea, bloating, abdominal pain (had to leave work and felt at one point might pass out on highway... pulled over)
8/4/18: woke up at night with nausea, vomited, up for an hour or two, eventually went back to bed
8/18/18: woke up at night with nausea, vomited, up for an hour or two, eventually went back to bed
9/8/18: woke up at night with nausea, vomited, up for an hour or two, eventually went back to bed
9/9/18: nausea, diarrhea, bloating

None of this has been associated with weight loss. My mother had a history of a very rare type of liver cancer. She had a liver transplant but eventually died of another unrelated cancer. Because of this, I opted to get a CT scan. CT found enlarged liver (right lobe span measuring up to 22.2cm) but no lesions. All else was normal. I thought it was my gallbladder and had an abdominal ultrasound (apparently that's better at visualizing the GB than CT?). Found two small liver hemangiomas not visualized on CT. GB was fine. I finally got in to see a GI specialist and he thought my liver issues were separate from GI issues. To investigate liver: Liver MRI (which has been done and was normal except my liver being large). To investigate GI issues: upper endoscopy/colonoscopy which will be happening in the next two weeks. Of note, most of my lab work has been normal (CMP, CBC with differential, sed rate, CRP, iron binding studies, amylase, lipase, celiac testing, LFT's besides Tbili). I had an unofficial diagnosis of Gilbert's Syndrome since grade school. I had a Total Bilirubin Panel done which showed elevated indirect bilirubin (evidence of Gilbert's). I also had a stool sample which was normal. I have biometric health screenings done annually for my employer's insurance plan and my blood pressure, cholesterol, lipid levels, and HbA1c are always normal. In fact, they tell me I'm their best numbers of the day. During this, I've also had my annual appointment with my OB and brought up my birth control. I've been on hormonal birth control for a total of 14 years. She said hormonal birth control does not put me at risk of liver issues, even with a history of benign liver problems. I still decided to stop taking my oral contraceptive pill.

I am at a loss of what else to try. I have no clue what could be making my liver so large. I would appreciate thoughts or perspectives. I found a semi-similar thread but it was very old and hadn't ever been updated by the OP.
Thank you in advance!

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