Discussions By Condition: I cannot get a diagnosis.

I would like to have a real diagnosis (possibly resistant TB?)

Posted In: I cannot get a diagnosis. 1 Replies
  • Posted By: Anonymous
  • April 29, 2007
  • 04:41 PM

i am a 46 year old male professional of indian origin. for the last ten years i have been getting intermittent fever, with pain in the left ear.

i used to be diagnosed as a case of upper respiratory tract infection and used to respond to various anitbiotics such as:
augmentin, erythromycin, ciprofloxacin etc...
in the last ten years i must have used antibiotics for about 30 - 40 times.
then i was given a long course of ciprofloxacicn for a month and later erythromicin for a month, however, symptoms started reccurring there for a tonsilectomy was done, which had no effect.

A cryptic TB was diagnosed and i received 4 drugs for approx 8 months.
Liver function tests were deranged hence the drugs were stopped, in ten days time symptoms reappeared. now i am on 3 drugs: INH, ethambutol, pyrazinamide. i am still symptomatic.

My symptoms are:
loss of apetite, loss of weight, cold extremities, severe malaise, arthralgias and unwellness (fever like but there is no fever), pain in left ear. Symptoms are worse in the evening. and there is a moderate improvement after eating.

My investigations so far are:
TT - positive at 27 mm
TB quantiferon gold test - positive.
biochemistry - normal
ESR was 27 but it's normal now
Plasma viscosity was raised at 1.91, now it's 1.62.
CT scan of thorax, abdomen, brain, sinuses - normal
x-ray of chest - normal
blood cultures - negative
antibodies screened for common viruses and bacteria - negative

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