Discussions By Condition: I cannot get a diagnosis.

Fever, sweats, chills, weight loss for 6+ months w/ all normal/negative test results. Any ideas?!

Posted In: I cannot get a diagnosis. 0 Replies
  • Posted By: Anonymous
  • April 3, 2020
  • 07:25 PM

CASE SUMMARY:
Ethnic background: Caucasian/White
Symptoms began: 7 months ago

BODY SYSTEMS AFFECTED:
* Abdominal or digestion (Primary Body Area Affected)
* Breathing
* Heart or cardiovascular
* Joint or muscular
* Mental health
* Skin or hair
* Whole body

SYMPTOMS DETAIL:
My primary symptoms include recurring abdominal cramping (i.e. 7/10) above the naval/below the sternum, unexplained weight loss (i.e. >20%), chronic fatigue, malaise, and recurring chills and low-grade fevers (i.e. <100 deg.F.). Shortness of breath and heart palpitations occur when the abdominal cramping is at its worst. I also suffer from night sweats, nausea and loss of appetite, feel foggy-headed on and off and have difficulty focusing on a task.

The abdominal cramping and nausea are usually worse upon waking in the morning and after meals and then resolve a few hours later.

The night sweats, chills and low-grade fevers are typically worse at night before I go to bed and while I sleep.

** Please note that diarrhea has never been and is not currently one of my symptoms. My stools are formed and normal in texture and color. **

CURRENT MEDICATIONS:
* Flonase Sensimist nasal spray 1 time daily for Seasonal allergies
* Azelastine HCl nasal spray 1 time daily for Seasonal allergies
* Optimum Nutrition Opti-Men multivitamin tablets 3 times daily for Nutritional supplement
* GNC Vitamin C 1000 mg tablets 2 times daily for Nutritional supplement
* Optimum Nutrition 100% Whey Gold Standard whey protein powder 2 times daily for Nutritional supplement

PERSONAL MEDICAL HISTORY:
I have never been hospitalized prior to this illness and only underwent a few minor surgical procedures. These include tonsillectomy when I was 2 years old, wisdom teeth extraction when I was 21 years old and a few other minor dental surgeries.

I was diagnosed with seasonal allergies as a child which have always been well-managed by Flonase Sensimist nasal spray, Azelastine HCl nasal spray and allergen immunotherapy (i.e. allergy shots). The seasonal allergies cause upper respiratory infections about twice a year when the seasons change (i.e. spring, fall).

Though I have never been formally diagnosed, I am a carrier of the human papillomavirus (i.e. HPV). I initially had active symptoms, but they disappeared over a decade ago.

FAMILY MEDICAL HISTORY:
My father was diagnosed with asthma, high blood pressure, depression, anxiety and severe sleep apnea about 10 years ago. He is 60 years old.

My mother was diagnosed with high cholesterol and diverticulosis about 2 years ago. She is 60 years old.

My younger brother was diagnosed with bee sting and monosodium glutamate (i.e. MSG) allergies as a child. He is 37 years old.

My maternal male cousin was diagnosed with Asperger's Syndrome (i.e. AS) as a child. He is 21 years old.

My maternal grandmother was diagnosed with breast cancer which eventually spread to other organs in her body when she was around 60 years old. She died around 63 years old.

I never met my paternal half aunt, but I learned that she was diagnosed with Lupus as a teenager. She died from complications of the disease at 33 years old. She and my father share a common father, but different mothers so it's impossible to tell whether this genetic disease could affect me.

DIAGNOSTIC OR IMAGING TEST ABNORMALITIES:
*** Stool Tests ***
All negative stool culture (x1), white blood cells (x3) and parasites (Cryptosporidium EIA x3, Cyclospora Smear, Stool x2, Ova + Parasite Exam x3 and Giardia Lamblia Ag, EIA x3)

*** Blood Tests ***
Hematology:
Slightly elevated WBC, MCV, absolute neutrophils, absolute monocytes and platelet count

Clinical Chemistry:
Slightly elevated calcium (CA) and BUN/creatinine ratio

Coagulation:
Slightly elevated D-dimer and anti-thrombin liquid

Immunology:
Slightly elevated C1q CIC, anti-histone and gliadin DP IgA

Endocrinology/Hormones:
Slightly elevated Vitamin B12

Lipids:
All normal

Thyroid:
All normal

Special Chemistry:
Slightly elevated apolipoprotein B/A1 ratio, and kappa lambda ratio; Slightly lowered lambda

Allergy:
Slightly elevated shrimp and alternaria alternata (i.e. mold)

Inflammatory Liver:
Negative

HIV/AIDS:
Negative

Hepatitis C:
Negative

*** CT Enterography ***
All normal findings

*** Capsule Endoscopy ***
Mild gastritis in the stomach and all normal findings in the small bowel and colon

*** Acute Abdomen Series X-Rays ***
All normal findings

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