Discussions By Condition: I cannot get a diagnosis.

Cause of cyclic neutropenia??

Posted In: I cannot get a diagnosis. 1 Replies
  • Posted By: Anonymous
  • August 26, 2008
  • 02:23 PM

My sister has been in and out of the hospital for cyclic neutropenia. She was first diagnosed with neutropenia after being ill (vomiting, fever, weakness) for over a week. Blood tests showed very low platelets, RBC, hemoglobin, hematocrit, leukocytes and neutrophils (neutrophils were 0.0). Bone marrow (done 3 times) showed normal cells, just few of them. Some cells later looked suspicious on one smear. Ultra sound showed a liver a tiny bit larger than normal and x-rays looked normal. She has been tested for many viruses, bacterias, leukemia and we have considered aplastic anemia. The doctors have no idea and have said they are 'stumped'. She was given antibiotics and monitored. Eventually she was taken off the antibiotics and her cell counts went back to normal (after being neutropenic for 1 1/2 weeks). 3 weeks later she became ill again with a fever that never breaks and was hospitalized for neutropenia again. This time only her neutrophils were very low (0.0). She has a constant fever and nausea which accompanies the fever. There is no bruising or tiny red dots and her bones do not hurt. The last bone marrow showed little to no fluid portion (we are waiting on the solid bone results). Currently they have her on fluids and tylenol and are monitoring her.

Her history;
16 years old
Had chicken pox
very anemic as a child (this was corrected)
vaccinated as an infant
leads a healthy lifestyle
fairly skinny (105lbs, about 5'3)
no known allergies

Reply Flag this Discussion

1 Replies:

Thanks! A moderator will review your post and it will be live within the next 24 hours.