Discussions By Condition: Poisoning

Psychological effects of DES

Posted In: Poisoning 1 Replies
  • Posted By: Anonymous
  • April 16, 2010
  • 04:39 PM

Have there been psychological effects noted in children exposed to DES while in the womb? I have heard that incresed sense of paranoia and extreme shyness have been reported. Thanks!

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  • Have there been psychological effects noted in children exposed to DES while in the womb? I have heard that incresed sense of paranoia and extreme shyness have been reported. Thanks!It's an old thread but I thought I'd reply anyway, in case anyone else is wondering. The short answer is yes, DES does appear to have produced quite a few psychological effects among many of those exposed to it in the womb, certainly as far as DES sons are concerned anyway. One of the effects of DES seems to be that it causes female brain development, which I think is by inhibiting testosterone synthesis. DES is a very potent chemical castration agent, and in adult men, just 3mg per day is enough to completely shut down male hormone production. The doses used for prevention of miscarriage were way beyond that. Even the pregnancy vitamin preparation "DES-plex" contained 25mg per tablet, more than enough to completely shut down testosterone production. Because of the way DES was typically prescribed, most of the effects were during the second and third trimester of pregnancy, which is the time when the brain undergoes most of its sexually dimorphic development. Based on what I've seen amongst other DES sons and what I've read about the crucial role hormones play in sexually dimorphic brain development, I think most if not all DES sons must have large parts of their brain that have developed as female. Exactly what is male and what is female probably varies quite a bit from person to person, depending on how far into the pregnancy the DES exposure started and ended. In my case I could tell I was somehow different from other people, but it wasn't in the slightest bit obvious what that difference was. It's only within the last couple of years that I've started to come to terms with, well, being partly a man and partly a woman is how I'd describe it.Extreme shyness is one of the things I had to deal with as a teenager, along with being bullied a lot. That seems to be quite a common experience among others in the DES sons in the support group I've joined too, perhaps because on the whole people tend to not react very well to feminine body language and behaviour coming from someone with a male body. Depression and "ADHD" seem to be really common problems too. I think when you have a situation where some brain regions have developed as male and others as female, they tend to not work together very well and that can give rise to a whole host of mental health problems, many of which are seemingly unrelated to gender. Your natural instinct is to try to suppress the female things to make yourself look and behave more like a typical man, and I think when that's carried on over a long period of time it starts to have really damaging psychological and neurological effects. Since I've stopped trying to suppress my feminine side, I've found that not only do I feel a lot happier and more "at peace" with myself, but my physical co-ordination along with my ability to use language and express myself all seem to have improved too.One other effect of these prenatal hormone exposures seems to be that they can mess up hormone regulation later in life. Like many of the DES sons in the support group, I've had lifelong low testosterone and problems with hypogonadism. This is something else to watch out for, particularly if you have a "eunuchoid habitus": feminine-looking facial features; long, slender arms and legs; legs that are significantly longer than your upper body; an armspan greater than your height; an inability to build upper body muscle; sparse body hair; a female pattern of pubic hair. Most doctors know zilch about hormones and are extremely reluctant to diagnose or treat hypogonadism in men, and some of the DES sons I've been in contact with have ended up crippled by osteoporosis as a result of untreated hypogonadism. Other problems commonly experienced by DES sons include infertility and physical intersex conditions such as undescended testes, hypospadias and micropenis. I think that, particularly for the DES sons whose exposure started early in the pregnancy, it often gave rise to a condition called "testicular dysgenesis syndrome", which results in intersexed development, reduced fertility and an increased risk of testicular cancer later in life. Unfortunately, very few DES sons seem to be aware of their status or the implications it could have for their health as they get older. There's a great deal of shame associated with intersex conditions, gender identity problems and mental health issues, which I think means very few DES sons are prepared to openly admit to or talk about the problems they're experiencing. The DES action groups seem to be run by DES daughters and that's where the focus of most of their efforts goes, while the medical profession seem to be doing their utmost to brush anything at all to do with DES sons under the carpet. The result is that there's no public awareness at all of the effects of DES on the DES sons, even though there are between 2 and 3 million of them worldwide, nearly all of whom I suspect are experiencing at least some problems resulting from their prenatal DES exposure.
    Anonymous 42,789 Replies
    • December 3, 2012
    • 04:41 PM
    • 0
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