Discussions By Condition: Poisoning

Fentanyl Toxicity & Fibromyalgia

Posted In: Poisoning 12 Replies
  • Posted By: Anonymous
  • February 18, 2008
  • 07:38 PM

My husband recently found his 35 year old sister passed away unexpectedly at her doorway. It was terrible. She suffered with Fibromyalgia, but was making great progress or at least we thought she was. She had just moved and was getting her life together again. She was happy. We just received the coroner's report and it was listed as an accident...blood reports showed fentanyl toxicity. She apparently abused the use of the patches for her pain. She was not suicidal...please be careful with use of these patches. Her new doctor wanted her to stop using the patches. Be aware, careful, and take care!

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  • There is no such thing as fibromyalgia, and there is no such thing as fentanyl toxicity except through massively extreme overdose.To overdose on an opioid like fentanyl would require a truly profound and expensive amount of the drug. It would take hours to die from it, and it would be easily curable at any point in that time with a single injection of naloxone, or another opioid receptor antagonist.It is essentially impossible to overdose on opioid analgesics unless it's intentional. The safety profile for opioids is extremely high. Fentanyl has a therapeutic index of over 200. By my math, someone would need to be wearing over 100 fentanyl patches of the highest potency to die of an overdose.
    bobwick 21 Replies
    • October 6, 2008
    • 01:56 PM
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  • UNLESS you use a heating pad. You forgot that little tidbit. Using a heating pad and cause a faster absorption into the blood and thus toxicity.Unfortunately for you, you've caused these people to think their sister was suicidal.Next time, get your facts straight before you open your mouth.
    Anonymous 42789 Replies
    • December 22, 2009
    • 08:34 AM
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  • UNLESS you use a heating pad. You forgot that little tidbit. Using a heating pad and cause a faster absorption into the blood and thus toxicity.Unfortunately for you, you've caused these people to think their sister was suicidal.Next time, get your facts straight before you open your mouth.I agree. Fibromyalgia is formally known as fibrositis, and exists in about 4% of people. I use fentanyl for this pain as well, and it is releatively easy to overdose on fentanyl, it supresses the breathing, and to say to die from this opiod you would have to wear a silly number of patches, as stated the patch can be accelerated with heat. Especailly if you have a fever, and the most important point is a patch can split or be cut (not with some types of patches but the resevoir type), releasing a torrent of the chemical onot your skin causing overdose.I cannot comment on your sister comiting suicide i am not a psychologist or seen the post mortem results, all i can say is i hope peace is with you.
    Anonymous 42789 Replies Flag this Response
  • There is no such thing as fibromyalgia, and there is no such thing as fentanyl toxicity except through massively extreme overdose.To overdose on an opioid like fentanyl would require a truly profound and expensive amount of the drug. It would take hours to die from it, and it would be easily curable at any point in that time with a single injection of naloxone, or another opioid receptor antagonist.It is essentially impossible to overdose on opioid analgesics unless it's intentional. The safety profile for opioids is extremely high. Fentanyl has a therapeutic index of over 200. By my math, someone would need to be wearing over 100 fentanyl patches of the highest potency to die of an overdose.Wow. I'm not a member of this site but was reading a related article in local news. I wasn't even going to reply to this but figured that on the off chance someone reads your post and decides abusing fentanyl is safe, that it would be negligent not to set you straight.Fentanyl is extremely dangerous when abused. Nearly all of the deaths from Fentanyl abuse come from chewing on the patches or even smoking small amounts of the gel. Some deaths from regular, legitimate users stem from defects in the patch that had allowed too much of the medication to be released.Your "facts" are so far off that it is almost laughable, if not for being so serious to have this kind of misinformation out there.A person can easily overdose on Fentanyl after chewing on just a small portion of a patch or even an empty patch. Likewise, wearing multiple patches can also result in an overdose, thought to say "100" patches is what it would take is beyond extreme. I would guess that it might only take a small fraction of that, in reality.And to say that it is nearly impossible to overdose on opioid analgesics is also extremely ignorant. The fact of the matter is that it is not all that difficult to overdose on prescription pain medication if it is misused. The dose on the prescribed directions are safe for who it is prescribed to, but anything above and beyond that can be dangerous and sometimes fatal. People who are opiate naive, however, can find themselves in serious trouble if they try to take the same amounts as someone who has been using opiates for any length of time, as there is a tolerance issue involved. Do some research. The information is easily available on the internet.As far as Naloxone goes, it is indeed effective and can reverse an opiate overdose, but it has to be given in time. Time being the key here. As opiate overdose usually results in respiratory failure, it doesn't take long before the Naloxone becomes useless.Fentanyl is very, very dangerous if misused.
    Anonymous 42789 Replies
    • December 8, 2010
    • 10:10 PM
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  • There is no such thing as fibromyalgia, and there is no such thing as fentanyl toxicity except through massively extreme overdose.To overdose on an opioid like fentanyl would require a truly profound and expensive amount of the drug. It would take hours to die from it, and it would be easily curable at any point in that time with a single injection of naloxone, or another opioid receptor antagonist.It is essentially impossible to overdose on opioid analgesics unless it's intentional. The safety profile for opioids is extremely high. Fentanyl has a therapeutic index of over 200. By my math, someone would need to be wearing over 100 fentanyl patches of the highest potency to die of an overdose.Mr. Junior member your post shows overwhelming ignorance on your part. Fibromyalgia IS a real medical condition that not one single patient enjoys having. Doctors treat patients for this life altering and painful condition. If you have a Phd and specialize in Rheumatology please let us know.As for your assumtion that this woman was intentionally trying to take her own life, I must say is shockingly heartless and cruel, especially for her family who is left here on earth to deal with their pain of losing their loved one. She posted on here to warn others to be careful. Shame on you.I am curious about your profession. Are you a Phd, RN, LPN or EMT? My guess is none of the above. I came to this conclusion because of your lack of knowledge about the real medical condition called Fibromyalgia and also because of your completely inaccurate explanation of opioid toxidity.These posts are read by many people on the internet for medical information. Including medication information. What if, sir, someone reading your post comes to the conclusion that as long as they don't stick 100 patches of Fentanyl to their body they will survive?
    Anonymous 42789 Replies Flag this Response
  • There is no such thing as fibromyalgia, and there is no such thing as fentanyl toxicity except through massively extreme overdose. To overdose on an opioid like fentanyl would require a truly profound and expensive amount of the drug. It would take hours to die from it, and it would be easily curable at any point in that time with a single injection of naloxone, or another opioid receptor antagonist. It is essentially impossible to overdose on opioid analgesics unless it's intentional. The safety profile for opioids is extremely high. Fentanyl has a therapeutic index of over 200. By my math, someone would need to be wearing over 100 fentanyl patches of the highest potency to die of an overdose. :( there is such a thing as fibromyalgia, fibro meaning fibrus tissue, such as muscle and tendons, myalgia meaning pain, it is a very hard to understand collection of bizzar symptoms, however there is such a term as fibro m.it is down to the fact that blood tests do not sshow any abnormalities or change that some doctors and specialist are sceptical about this mysterious condition, but ask anyone who as suffered this and they will tell you it does exist. please believe me if i could wake up one day and feel healthy and normal i would be very happy, i love life and want to do something with it now my son,s have grown up , but i am held back by the bizzar effects of this mystery illness. no-one who wants to live to the full would actually be able to imagine that they have this going on with their body , as suggested by many people. please may i add, in response to your comment, no such thing as fentanyl poisoning, when someeone suffers witth fibro, they are chemical sensitive, so therefore, maybe you are wrong on this one too, i am very sensitive to lots of things chemical wise, since having my illness, i have reacted unusually to thing i would normally be able to tolerate.susan marie.
    susan marie 3 Replies Flag this Response
  • There is no such thing as fibromyalgia, and there is no such thing as fentanyl toxicity except through massively extreme overdose. To overdose on an opioid like fentanyl would require a truly profound and expensive amount of the drug. It would take hours to die from it, and it would be easily curable at any point in that time with a single injection of naloxone, or another opioid receptor antagonist. It is essentially impossible to overdose on opioid analgesics unless it's intentional. The safety profile for opioids is extremely high. Fentanyl has a therapeutic index of over 200. By my math, someone would need to be wearing over 100 fentanyl patches of the highest potency to die of an overdose. :mad:. there is such a condition as fibromyalgia, fibro meaning soft tissue , such as muscle and tendon and myalgia meaning pain in these areas, this is a very bizzar illness that can truly knock you off your feet, it was once questioned by medical experts because blood tests do not show abnormalities, however medical research as discovered that fibro m does exist. in response to your theory on fentanyl poisoning, please may i add that a fibro myalgia sufferer becomes very sensitive to chemicals, so therefore what she was prescribed may well have had this devestating effect, i have been very chemical sensitive since becomming ill, i cannot tolerate medication i used to be able to take, i have had some unusual reactions.susan marie.
    susan marie 3 Replies Flag this Response
  • While I can't support the assertions regarding fentanyl toxicity, there is still much debate whether "fibromyalgia" is in fact a disease, a condition, or merely a constellation of symptoms. The word itself is somewhat suspicious- fibro (fibrous material in the body) and myalgia (pain). http://abcnews.go.com/Health/PainManagement/story?id=4138715&page=2The originator of the term used it to express to patients having these symptoms that they suffered from an actual medical condition. This was important for patients to accept and allow treatment for their pain. He has subsequently disavowed intending for "fibromyalgia" to become a recognized disease, but merely confirmational that some patients have unexplained pain. (Maybe what used to be called "aging".)
    Anonymous 42789 Replies Flag this Response
  • The National Institutes of Health has classified fibromyalgia as a disease (2009) after electron microscopy revealed "moth-eaten" muscle fibers and clusters of dead mitochondria were found at the terminal point of muscle fibers w/ patients diagnosed as having fibromyalgia. Further, the gene common to all patients w/ this disease has been identified. Fentanyl overdose is potentially fatal, as are all opiates due to the effect on the cardiopulmonary system. The "junior member" responding above is obviously uninformed and may have mislead opioud users into a false sense of security which is quite dangerous.
    SoulGardener 1 Replies
    • January 28, 2012
    • 03:32 AM
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  • I am sorry to hear about what happened to your step daughter.
    Back pain doctor 6 Replies
    • February 16, 2012
    • 03:38 PM
    • 0
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  • There is no such thing as fibromyalgia, and there is no such thing as fentanyl toxicity except through massively extreme overdose.To overdose on an opioid like fentanyl would require a truly profound and expensive amount of the drug. It would take hours to die from it, and it would be easily curable at any point in that time with a single injection of naloxone, or another opioid receptor antagonist.It is essentially impossible to overdose on opioid analgesics unless it's intentional. The safety profile for opioids is extremely high. Fentanyl has a therapeutic index of over 200. By my math, someone would need to be wearing over 100 fentanyl patches of the highest potency to die of an overdose.Dear sir, As someone who has battled M.E. and FMS for 39+ years I am quite prepared to show how completely wrong you are on our first comment regarding fibromyalgia. But I'm used to trolls by this point and am currently dealing with a much bigger issues...your comments regarding fentanyl could kill someone they are so wrong. How do I know this? I can provide you with my 20 year old son's death certificate, whom I just buried two weeks ago. Or if you should be so disrespectful as to suggest that my son was somehow responsible, not knowing anythng about the case yourself, then merely research it through the FDA itself. They KNOW the patches are unsafe. There have been multiple recalls, Thousands of deaths and yet for reasons God only knows and we can all guess..they have sat back and the only action taken has been to have their watch dog keep an eye on the companies and the product...I have to ask..why didn't they stop it sooner so my son would still be here? How many deaths does it take before it's murder? They will all go home tonight a bit wealthier, play with their children, hug their families and my son's name won't even ring a bell to them. They won't lay in bed longing for him to pop his head in and tell them "good night mom Love you!" No, they got their money. I however lost my son due to their greed and they won't lose one wink of sleep over it. People need to know just how dangerous fentanyl patches are. I deal with daily pain myself. I push strongly for better pain management but it's got to be safe..and these are not. I cannot plead with you enough...if you are on these patches PLEASE realize the great risk you are taking and try a different avenue
    MourningMother 2 Replies
    • February 29, 2012
    • 10:10 AM
    • 0
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  • While I can't support the assertions regarding fentanyl toxicity, there is still much debate whether "fibromyalgia" is in fact a disease, a condition, or merely a constellation of symptoms. The word itself is somewhat suspicious- fibro (fibrous material in the body) and myalgia (pain). http://abcnews.go.com/Health/PainManagement/story?id=4138715&page=2The originator of the term used it to express to patients having these symptoms that they suffered from an actual medical condition. This was important for patients to accept and allow treatment for their pain. He has subsequently disavowed intending for "fibromyalgia" to become a recognized disease, but merely confirmational that some patients have unexplained pain. (Maybe what used to be called "aging".)I first became ill at the age of 13. Was finally dx'd at the age of 16 and have only got progressively worse. I was not "lazy". Despite my disease I graduated with honors a year early and started college on my 16th birthday. Would you call this "aging"? Now depending on the presenting symptoms at the time I am also dx'd with ME ( CFS), another disease some claim is the same others say is different than FMS but still faces the same ignorance. Itis difficult enough to adapt one's life with the pain and unimmaginable exhaustion and other myriad of symptoms I face daily but to have to defend one's character as well to people who have no clue only makes it worse. What I would like to know is WHY is it any concern of yours? Do you have nothing better to do than go around "virtually" kicking very sick people and their families who are already struggling to exist? Let's suppose that it is a mental illness (WHICH IT IS NOT..AUTOPSIES HAVE PROVEN IT TO BE OTHERWISE) BUT let's give you that..mental illness is still a severe illness, one which your bullying could have horrible reprocussions. So again I ask..Why you feel the need to go around throwing your extremely wrong, very uneducated two cents on this subject in? Have you given ANY thought to the harm you could be doing?
    MourningMother 2 Replies
    • February 29, 2012
    • 06:14 PM
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