I have had recurrent mouth ulcers and skin lesions on arms, hands and sometimes feet for the past 6 years. I have had all bloodworm done, biopsies done, tests, etc. and they have all come back negative/inconclusive. I have also tried a variety of medications including dapsone, imuran, valtrex, etc. and I have had no relief. I have had to take prednisone every month to help with the inflammation because the mouth ulcers become so severe after a week that I cannot eat, talk, brush my teeth, etc. I'm at a loss of what to do next and would like to know if anyone has any thoughts or ideas. Please share. Thank you!