vitamin B12 is a water-soluble vitamin that is normally existing in some meals, included to others, and available as vitamins and a drugs. Complement B12 prevails in several types and contains the nutrient cobalt , so substances with vitamin B12 action are jointly known as "cobalamins". Methylcobalamin and 5-deoxyadenosylcobalamin are the types of vitamin B12 that are effective in individual metabolic rate . Vitamin B12 is needed for appropriate red blood vessels mobile development, nerve operate, and DNA features . Complement B12 features as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase. Methionine synthase catalyzes the transformation of homocysteine to methionine . Methionine is needed for the development of S-adenosylmethionine, a worldwide methyl contributor for almost 100 different substrates, such as DNA, RNA, testosterone, necessary proteins, and fats. L-methylmalonyl-CoA mutase transforms L-methylmalonyl-CoA to succinyl-CoA in the deterioration of propionate , an important biochemical response in fat and proteins metabolic rate. Succinyl-CoA is also needed for hemoglobin features.