Discussions By Condition: Medical Stories

weird blood work - high HDL & low B12

Posted In: Medical Stories 11 Replies
  • Posted By: specialblackdoggie
  • May 29, 2007
  • 02:13 AM

My doctors are trying to figure out what is wrong with me. I am mid-forties, female, 5'7", 135 pounds, healthy appearance. The results from my most recent two sets of blood work include the following:

First set:
=========
cholesterol - 6.30 mmol/L (HDL & LDL not done)
T4 free - 9 pmol/L

RBC Indices:
MCV - 102
MCH - 36

RBC's - Macrocytosis - mild

Second set (8 days after the first set):
=============================
Cholesterol - 7.28
Triglycerides - 0.70
HDL - 3.35
LDL - 3.6
TC/HDL-C ratio - 2.2

Vitamin B12 - 106

*** all other results were in the normal range ***

I'm losing sleep worrying while I get referred to different specialists - please help! Thanks!

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11 Replies:

  • Specialblackdoggie I am not an expert by no means (is that a double negative:confused: ); however, I believe your B-12 is too low. Please look at the thread in tell us your medical story: Vitamin B12 deficiency is commonly misdiagnosed. By Sally Pacholok, BSN. http://forums.wrongdiagnosis.com/showthread.php?t=9948 Since you didn't say what your symptoms were, but you did say DR's don't know whats wrong with you, please read this thread. I think if is applies you will be intrigued within the first page. Cala
    Cala1234 57 Replies Flag this Response
  • What sticks out like a sore thumb are the MCV of 102 and the MCH of 36. These indicate likely methylb12 deficiency and/or folate deficiency. Daily oral methylb12. 1mg or 5 mg should do the trick. Also, a b-complex and additional folic acid totalling 1600mcg daily. Rapid cell formation can cause depletion of all sorts of things like potassium which can cause a problem. Zinc, A,D, C, E, magnesium, omega3 oils all can be lacking enough to limit the effectiveness of the methylb12. Methylb12 is the actual real immediately active form of b12. The inactive cyanocobalamin and hydroxycobalamin both have to be converted. You serum level is very very low. If you take one of the effective sublingual methylb12 brands you may feel an effect within 10 minutes, many do. Whatever else is wrong it is urgent that you start methylb12 as soon as possible along with folic acid or methylfolate. The is a prescription your doc can give you for Metanx, which contains methylfolate, methylb12 and P-5-P. You should also have a b-complex and potassium. Those extremely low serum levels of b12 probably indicates that you don't absorb or retain b12 normally or you are a vegan.
    Freddd 3576 Replies Flag this Response
  • Specialblackdoggie, I have posted a reasonably complete list of symptoms, signs and correlating conditions on the difficulty diagnosing b12 thread. It's on page 42. Take a look at that and see what else lines up besides MCV and MCH. I would like to offer one caution. The experience of taking an active brand of methylb12 can be a very intense experience initially. Don't let that frighten you. As your serum level comes up and your body gets used to that higher level, the intensity diminishes. Often symtoms are intensified at first before healing. I used to have chronic daily headaches and really intense 3-5 day killers each two weeks. The headaches were related to "veins of fire" in my scalp and muscle spasms in neck and head. The headaches got more intense for a while then faded away completely, as in 100% except for dental work. All of the neuropathies that I have had heal have gone backwards through the symtoms. On the way out the feelings went from "cobwebs" to tingles and more intense feelings to pain to numbness. On the way back from numbness it went to intense shooting pains (about two days for each specific area changed), then pain, then the intense sensations, then tingles, then cobwebs. Injectable methylcobalamin, available by prescription at a compounding pharmacy, has a similar effect to an active sublingual only even more intense. A 10 ml vial with 250mg of methylb12 costs about $100. I use the .3ml 31 gauge 5/16 inch insulin syringe for subcutanous injections. One vial lasts me just short of 2 months. I inject every day and so far, after 12 months I am retaining the most I ever have with no signs of having saturated a system. Methylfolate nearly doubled the amount I could inject before it shows up in my urine. Good luck
    Freddd 3576 Replies Flag this Response
  • It will be good to consult the doctors when your reports are not normal. If the doctor suggests any specialist then should get the consultation from their too. I will even suggest you to go for the thyroid test which normally is not given much importance and ignored. T1, T2, T3 and TSH. I think it should make the picture more clearly about your health. The possibility of menopausal syndromes is high in this age so take advice in that direction too since you are in mid forties. Please post the updates of your treatment.
    sapnil 9 Replies
    • February 14, 2011
    • 06:15 AM
    • 0
    Flag this Response
  • I know that this an older post, but I'm kind of going through the same ordeal now and I happened to stumble upon THIS thread in Google. I had always considered myself a relatively healthy individual, but I guess my own blood tests dictated otherwise. The fact that I, myself, am being sent over to specialists is nothing short of scary -- believe me!Now. . . I DID read this post, and I became rather intrigued with the idea of supplements:Specialblackdoggie I am not an expert by no means (is that a double negative:confused: ); however, I believe your B-12 is too low. Please look at the thread in tell us your medical story: Vitamin B12 deficiency is commonly misdiagnosed. By Sally Pacholok, BSN. http://forums.wrongdiagnosis.com/showthread.php?t=9948 Since you didn't say what your symptoms were, but you did say DR's don't know whats wrong with you, please read this thread. I think if is applies you will be intrigued within the first page. Cala While I think it's best that I'm being sent to specialists that will help me out, I can't help but think that you may be onto something, Cala. I'm not entirely sure if I'm deficient in any B-vitamins, but I'll definitely talk to my doctor about the possibility of consuming extra supplements. Do YOU take any supplements, Cala? I know that there's a whole variety of them out there -- Centrum, One-a-Day, Nature's Bounty, etc. However, I want to make sure that I'm taking the right ones for ME. Has anyone perhaps taken Purest Colloids (purestcolloids.com) supplements before? I've only heard about them recently through the internet. Thanks, guys! =)
    AHealthyLife 4 Replies Flag this Response
  • One more question, did you ever get your condition figured out, specialblack? Thanks. =)I actually found this interesting article concerning b-2 injections. Check it out, why don't ya? http://www.ahwatukee.com/healthy_living_2011/article_acfe6164-4148-11e0-bcf7-001cc4c002e0.html
    AHealthyLife 4 Replies Flag this Response
  • I realize that this a very old post, but I just wanted to say that I'm very glad to have found this thread. Initially, I thought that I was a healthy person (and yeah. . . I'm somewhat happy), but apparently I need to see a few specialists myself. My blood tests are fairly similar -- so the thought or idea of a b-12 deficiency being prominent is definitely something to think about it. I'll certainly talk to my doctor about taking a b-12 supplement (thank you, Cala1234) in order to get my body "back on track." I've been taking One-A-Day vitamins, but I don't know how well it helps with the alleged deficiency. Has anyone ever tried purest colloids before? I'd love to hear your experiences if anyone has done so. Thanks a lot, guys! =)
    AHealthyLife 4 Replies Flag this Response
  • I realize that this a very old post, but I just wanted to say that I'm very glad to have found this thread. Initially, I thought that I was a healthy person (and yeah. . . I'm somewhat happy), but apparently I need to see a few specialists myself. My blood tests are fairly similar -- so the thought or idea of a b-12 deficiency being prominent is definitely something to think about it. I'll certainly talk to my doctor about taking a b-12 supplement (thank you, Cala1234) in order to get my body "back on track." I've been taking One-A-Day vitamins, but I don't know how well it helps with the alleged deficiency. Has anyone ever tried Purest Colloids (www.purestcolloids.com) before? I'd love to hear your experiences if anyone has done so. Thanks a lot, guys! =)
    AHealthyLife 4 Replies Flag this Response
  • My doctors are trying to figure out what is wrong with me. I am mid-forties, female, 5'7", 135 pounds, healthy appearance. The results from my most recent two sets of blood monitor include the following:First set:=========cholesterol - 6.30 mmol/L (HDL & LDL not done)T4 free - 9 pmol/LRBC Indices: MCV - 102 MCH - 36RBC's - Macrocytosis - mildSecond set (8 days after the first set):=============================Cholesterol - 7.28Triglycerides - 0.70HDL - 3.35LDL - 3.6TC/HDL-C ratio - 2.2Vitamin B12 - 106*** all other results were in the normal range ***I'm losing sleep worrying while I get referred to different specialists - please help! Thanks! It will be good to consult the doctors when your reports are not normal. If the doctor suggests any specialist then should get the consultation from their too. I will even suggest you to go for the thyroid test which normally is not given much importance and ignored. T1, T2, T3 and TSH. I think it should make the picture more clearly about your health. The possibility of menopausal syndromes is high in this age so take advice in that direction too since you are in mid forties. Please post the updates of your treatment.
    sapnil 9 Replies Flag this Response
  • It will be good to consult the doctors when your reports are not normal. If the doctor suggests any specialist then should get the consultation from their too. I will even suggest you to go for the thyroid test which normally is not given much importance and ignored. T1, T2, T3 and TSH. I think pulse oximeter should make the picture more clearly about your health. The possibility of menopausal syndromes is high in this age so take advice in that direction too since you are in mid forties. Please post the updates of your treatment.
    sapnil 9 Replies Flag this Response
  • Specialblackdoggie I am not an expert by no means (is that a double negative:confused: ); however, I believe your B-12 is too low. Please look at the thread in tell us your medical story: Vitamin B12 deficiency is commonly misdiagnosed. By Sally Pacholok, BSN. http://forums.wrongdiagnosis.com/showthread.php?t=9948 Since you didn't say what your symptoms were, but you did say DR's don't know whats wrong with you, please read this thread. I think if is applies you will be intrigued within the first page. CalaI agree with Cala. Your Vitamin B12 could be an issue. I'm not a doctor but I saw on the Today show that lots of people are deficient of B12. I went to the doctor and they did a blood test where they can tell you what vitamins you need more of and I was way low on B12 too. Most short term health insurance plans should cover the test too. Check with your doctor to see if they can do the test for you.
    JakeJohnson25 6 Replies Flag this Response
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