I am a 55 year old Hindu male with a black complection. I am 5' 4" and weigh 58 kgs. I am a moderate smoker. I am a private medical practitioner for last 28 yrs.
I have complains of recurrent blood with mucus in the stool and fatigue and malaise at least thrice a year from 1982. Single adenomatous polyp in rectum less than 2 cm was operated in 1996 but symptoms persists. Latest Proctoscopy in 2004 showed no recurrence of polyp but mild immunological erosion in rectum was present. Renal stone in 1998 passed after plenty of water intake. Again renal stone after 6 years occured. Ultrasonography K.U.B. showed 4 m.m. stone at right utero vesical junction. After 2 months ultrasonography showed no Ureter dilatation. But yet i have not yet passed a stone. IVP was not done. In last year i developed a fungus like lesion mainly in the lower limbs which was not releived by antifungal drug- Itraconazole (100mg weekly for 4 weeks). Biopsy revealed focal inflammation (but not Koch's lesion). Skin lesions are on the way of healing. This skin lesions used to occur previously at a mild stage but recurrently. Lesion responded to local steroids. For last eight years i had become Hypertensive. My Cholestrol level and Trglyceride level is higher. My latest LDL cholestrol is 160. I am not taking Atorvastatin tablet. Angiotensin converting enzyme level is 92(a little higher. Estimation of uric acid and calcium in 24 hrs urine is a little higer. I am suffering from Normocalcaemic hypercalciuria. My uric acid level and creatinine level is normal. I am not suffering from Anaemia or any gross weight loss. I am not diabetic. I have family genetic history of carcinoma. My mother died of Cholangiocarcinoma of bile duct. My elder brother recently died of Non Hodgkin's lymphoma.
I want to know that are these symptoms indicate to any particular disease or separated multiple ones. What further investigation i need to do and what will be my further course of treatment.
Kindly reply with your suggestions.
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