I was diagnosed with collagenous colitis in 2002. I was told that there was no cure for this disease. At the time, I was taking Paxil for depression. I had chronic diarrhea for over two years, up to 33 bowel movements per day. I stopped taking Paxil, and within 6 weeks, the diarrhea had partially subsided. Within 6 months, it was gone! I had another colonoscopy, and was pronounced colitis-free.
The following year, I began taking Paxil once again. Within a week, the diarrhea was back with a vengeance. I immediately stopped taking Paxil, but it was a full six months before the diarrhea fully subsided. Has anyone else had a similar experience, or am I just extremely sensitive to the drugs in Paxil?