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Allergic to vitamin B12

Posted In: Medical Stories 5 Replies
  • Posted By: Anonymous
  • September 8, 2007
  • 11:39 PM

I am unable to take foods or vitamins that have high amounts of B12 in them. I can find nothing on the web that can tell me why this might be the case. My doctor says my B12 is low and I must take shots but I am afraid to do that since fortified foods and vitamin pills cause horrible stomach problems and depression. I would love to hear from anyone else who might have some answers to my problem.

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  • I am unable to take foods or vitamins that have high amounts of B12 in them. I can find nothing on the web that can tell me why this might be the case. My doctor says my B12 is low and I must take shots but I am afraid to do that since fortified foods and vitamin pills cause horrible stomach problems and depression. I would love to hear from anyone else who might have some answers to my problem.I actually experience a similar thing. I get really sleepy with just 50% DV of B12. So much for an energy vitamin. I hope you can figure this out for the both of us!
    Anonymous 42789 Replies Flag this Response
  • First off, the question come up "what kind of "b12"? cyanocobalamin, the most common vitamin form can make some people sick. If you have actually managed to find one of the effective brands of effective kinds and taken it in an effective way, you might have startup reactions caused by up to hundreds of things starting to function at once which can be unpleasant and cause an intensification of symptoms. Come on over to the http://forums.wrongdiagnosis.com/showthread.php?p=227227#post227227 and learn about the effects of real b12 and how to use it and it's effects. I sincerely doubt that you are actually allergic to b12 though it is possible that cyanocobalamin could cause you problems and methylb12 could cause startup reactions that you might interpret as "bad" reactions. And read the basics http://forums.wrongdiagnosis.com/showthread.php?t=62327 REASONS WHY B12 THERAPIES DON'T WORK FOR MANY PEOPLEVersion 1.0 - 07/19/091. They take an inactive b12, either cyanob12 or hydroxyb12. The research “validating” their use was primarily for reducing blood cell size in Pernicious Anemia, keeping the serum b12 level over 300pg/ml at the end of the period between injections. They make a statistically significant effect that can be seen in lab tests in a significant percentage of people compared to placebo. They do not heal most damage done by active b12 deficiencies and have little or no effect on the vast majority of symptoms. They may even block active b12 from receptor sites hindering the effects of real b12. They both cause a keyhole effect of having only a very limited amount (estimated at 10mcg/day) that can actually be bound and converted to active forms. They in no way increase the level of unbound active cobalamins which appear required for most healing. They do nothing beneficial in a substantial percentage of people (20-40%) while giving the illusion that the problem is being treated and if it doesn’t work, oh well, that’s the accepted therapy. There is no “dose proportionate” healing with these inactive b12s because it all has to go through this keyhole. Some people are totally incapable of converting these to active forms because they lack the enzyme2. They take active b12 as an oral tablet reducing absorbtion to below 1%. A 1000mcg active b12 oral tablet might bind as much as 10mcg of b12. Again the b12 has to be squeezed through a keyhole that limits the amount and is subject to binding problems in the person whether genetic or acquired.3. They take a sublingual tablet of active b12 and chew it or slurp it down quickly reducing absorbtion back to that same 1% and limited to binding capacity. With sublingual tablets absorbtion is proportionate to time in contact with tissues. I performed a series of absorbtion tests comparing sublingual absorbtion to injection via hypersensitive response and urine colorimetry.4. Of the many brands of sublingual methylb12 only some are very effective. Some are completely ineffective and some have a little effect.5. For injectable methylb12, if it is exposed to too much light (very little light actually is too much) it breaks down. Broken down methylb12 is hydroxyb12. It doesn’t work at healing brain/cord problems of those who have a presumed low CSF cobalamin level. That requires a flood of unbound methylb12 and adenosylb12 (2 separate deficiencies) that can enter by diffusion. Adenosylb12 from sublinguals can ride along with injected methylb12.6. They don’t take BOTH active b12s.7. They don’t take enough active b12s for the purpose.8. Lack of methylfolate9. Lack of other critical cofactors.10. Lack of basic cofactors.
    Freddd 3576 Replies Flag this Response
  • I actually experience a similar thing. I get really sleepy with just 50% DV of B12. So much for an energy vitamin. I hope you can figure this out for the both of us! And then specifically for you, methylb12 causes an increase in melatonin and normalization of sleep. SOme people do respond by getting sleepy, it is a healthy response.
    Freddd 3576 Replies Flag this Response
  • I am having trouble with vitamin b12 too! I suffer from anxiety, depression, and now intrusive thoughts that go along with them. My anxiety has disipated quite a bit with therapy. I used to have 3 panic attacks a day. Now I hardly have them at all.I had a vitamin D deficiency which has been corrected but my naturapathic doctor (which I am seeing because meds haven't really worked for me) said B12 might help me. He gave me this intrinsi factor b12 with folate and after taking I felt like I was having the WORSE panic attack of my life. I was shaking, confused, panic through the roof. I didn't think vitamin b12 could do this! It was the cyanocobalamin and I had been taking 500mcg twice a day. I was so bad that my neighbor wanted to take me to the hospital and I almost went and she has seen me have panic attacks before! So the ND had told me to take magensium with it and I should feel better. I did and all that it made me was nauseous on top of the edgy feeling I felt. (Note: I took a lorazepam and it helped a little when it usually knocks out a panic attack.) This disipated but lasted for a few days after I stopped taking the vitamin. I tried it again yesterday after not being on it for two weeks. I tried a different brand w/o the intrinsi factor or folate because I thought it might be them. I thought NO way can b12 do this, but again I got the same results. Is this normal? Could something else be wrong with me? I would appreciate any feedback. Thanks!NOTE: Basically everything medical has been checked and scanned. Thyroid, and what not, but I should let you know my b12 has not been checked the ND just thought it might help or make a difference.
    ksavage5 1 Replies Flag this Response
  • I am having trouble with vitamin b12 too! I suffer from anxiety, depression, and now intrusive thoughts that go along with them. My anxiety has disipated quite a bit with therapy. I used to have 3 panic attacks a day. Now I hardly have them at all.I had a vitamin D deficiency which has been corrected but my naturapathic doctor (which I am seeing because meds haven't really worked for me) said B12 might help me. He gave me this intrinsi factor b12 with folate and after taking I felt like I was having the WORSE panic attack of my life. I was shaking, confused, panic through the roof. I didn't think vitamin b12 could do this! It was the cyanocobalamin and I had been taking 500mcg twice a day. I was so bad that my neighbor wanted to take me to the hospital and I almost went and she has seen me have panic attacks before! So the ND had told me to take magensium with it and I should feel better. I did and all that it made me was nauseous on top of the edgy feeling I felt. (Note: I took a lorazepam and it helped a little when it usually knocks out a panic attack.) This disipated but lasted for a few days after I stopped taking the vitamin. I tried it again yesterday after not being on it for two weeks. I tried a different brand w/o the intrinsi factor or folate because I thought it might be them. I thought NO way can b12 do this, but again I got the same results. Is this normal? Could something else be wrong with me? I would appreciate any feedback. Thanks!NOTE: Basically everything medical has been checked and scanned. Thyroid, and what not, but I should let you know my b12 has not been checked the ND just thought it might help or make a difference.Hi Ksavage,You might want to try one of the two 5 star methylb12. The response might be something entirely different. Or it m,ay be that the cyanocobalamin is acting as b12 for you and you respond to increased energy production and increased nervous system activity with anxiety. Anxiety is frequently a b12 deficiency symptom and many symptoms increase intensity at first. Some people with this response find that magnesium helps. The "edgy" feeling is the nerves and mitochondria coming back on line. It passes after a while. One thing that may help is to get the 1mg Jarrow methylb12 sublinguals and take a crumb of it at a time. You can build up slowly and eventually get things started up. Another possiblility is to take a the 5mg methylb12 Jarrow, and take 3 or 4 of them a day for a few days. Dropping back to the 1mg then will likely be a non-event. The effect of mb12 falls off rapidly. The effect is not linear. 2mgs is not twice as stimulating as 1mg. It's more like 10mg might be twice as stimulating as 1mg. The effect falls off rapidly.Read the basics at http://forums.wrongdiagnosis.com/showthread.php?t=62327&page=2 and then come on over to talk with a lot of people with a lot of experience in all this at http://forums.wrongdiagnosis.com/showthread.php?t=9948&page=411.
    Freddd 3576 Replies Flag this Response
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