My 13 year old son has been sick frequently for 2 years now. We have been to tons of doctors. He has many symptoms, but what I'm most concerned about are his recurrent fevers. Sometimes he will have a fever for several days - 2 weeks with no other symptoms or sometimes with a headache. Several drs have mentioned lupus and have done the ANA tests but they have come back negative. I've heard that sometimes you can still have lupus even if the blood tests don't show. Are fevers and/or headaches among the lupus symptoms? He was in the hospital last week with a possible allergic reaction. He had hives, swelling, fever, protein in urine and his blood protein level was low.