Discussions By Condition: Liver conditions

Liver Function Tests - raised GGT and ALP - Whats going on ???

Posted In: Liver conditions 1 Replies
  • Posted By: andrea5867
  • June 25, 2011
  • 09:34 PM

Three weeks ago my partner was sent home from work feeling extremely ill with pains in his abdomen
They didnt improve and he was admitted to hospital three days laterwith suspected Gallstones and / or infection in his gallbladder. An ultrasound showed no stones present and he was given IV antibiotics for 4 days He is really weak, unable to walk far or fast and still in considerable pain
The hospital requested he stay in over last weekend in order that he see a liver specialist immediately on monday due to elevated test results but an appointment was never followed up and he was discharged after 10 days with no idea what is wrong other than some problem with his liver
Five days later he is no better, still in considerable pain with little or no energy. He says it feels like there is a pressure in his abdomen and when the pressure builds up so does the pain
His test results in the main stabilised with the exception of two LFT levels that continued to rise from admission to the time of his discharge
Can anyone tell us what these may mean ...
GGT normal range 0-50..... 581 0n 16/6 rising to 937 0n 18/6 (latest test result)
ALP normal range 30-130..... 272 0n 16/6 rising to 365 on 18/6
No follow up bloods have been ordered since 18/6
He is not a drinker - last drink was probably aroud Easter and before that months ago - wasnt a big drinker in the past and eats pretty well plus has a quite physical job
The only thing we can say is that theres maybe been a problem for a few months in hindsight as he has been physically drained all the time - he's 47 years of age by the way
Should there be anything we should be concerned about and has anyone experienced something similar
Hepatitis and AFP tests all came back fine too

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  • Those are some pretty high enzymes! I'm not a doctor, but from what I know, these enzymes are released when liver cells are damaged and are replaced by new ones. High enzymes indicate something is irritating the cells, causing them to die and be replaced at a rapid rate. High spikes like this are not too dangerous as long as they do not last too long, or keep climbing. He needs to be followed up by his GP, have enzymes drawn and tested again, and referred to a hepatologist if they are not falling fast enough. You mention a "physical job"... Does he take a lot of pain meds? Tylenol (aka acetaminophen or paracetamol) can cause liver problems if it is taken in high doses or if his diet does not contain enough nutrients to break down the toxic metabolites of this drug. Prescription pain meds can also contain a lot of acetaminophen too that may not be easy to notice on the label. A toxic exposure can also hurt your liver pretty bad. Does he work with solvents at work? Hemochromatosis is a genetic iron overload problem that often shows up in mid life. He should have been checked for this in the hospital (a simple blood test). It is easily treated, but is very dangerous when it is not treated. Livers love Lecithin (phosphatidylcholine) found in eggs... It should be safe to try a couple of these a day for a while and see if it helps. Ask his doc about this when you get in to see him. He really needs to be followed up as an outpatient to be sure this is resolving. Your liver is nothing to play around with. Good Luck and GodSpeed to you.
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