Creatinine is the metabolite of muscles in human bodies, every 20g muscles can be metabolized to 1mg creatinine. It is mainly filtrated by glomerulus to be excreted out of the body. The creatinine in blood is classified into the exogenous and the endogenous. Exogenous creatinine is the metabolite of meat in human bodies; exogenous creatinine is the metabolite of muscles in human bodies. If the intake of meat is stable and there is no big change of muscles metabolite, the production of creatinine will accordingly keep stable. The normal value of serum creatinine: 88.4—1 76.8μmoI/L. Since the examination devices are dissimilar of different hospitals, the reference ranges may be a little different. Generally, the normal value of serum (plasma) creatinine is: male: 53—106μmoI/L, female: 44—97μmoI/L. Under the conditions above, if the creatinine shows an upward trend, the consistency change of serum creatinine should be related with the filtration ability of glomerulus. Glomerular filtration ability dropping means the kidney can not effectively excrete the toxins (such as creatinine and blood urea nitrogen) and waste normally, then the consistency of creatinine will increase.Reply Follow This Thread Stop Following This Thread Flag this Discussion
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