Discussions By Condition: Immune conditions

DNA Study for Wegener's Granulomatosis Patients

Posted In: Immune conditions 2 Replies
  • Posted By: clinical genetics
  • June 9, 2009
  • 03:42 PM

DNA Study for WG Patients
Blood Donations Needed

The goal of Dr. Katherine Siminovitch’s study: ‘Identification of Novel Wegener’s Granulomatosis Susceptibility Genes’ is to identify the genes that confer risk for disease. The study has already identified variants in three of the genes studied and determined them to be significantly associated with WG. While we are continuing to assess other gene variants for their relevance to WG, the study needs at least 250 more WG patients to donate samples to have sufficient data to develop results.

It is very simple to participate in the study. Patients enroll in the study and have a blood sample drawn at their doctor’s office or laboratory and shipped to Dr. Siminovitch with the materials provided. If it is not convenient for you to have your blood drawn, we can send you a saliva kit – the saliva sample can be done in your own home.

Identification of WG susceptibility genes will provide a promising avenue to the development of improved diagnostic and prognostic tests, as well as new targets for therapeutic management.

All WG patients are eligible for the study, regardless of geographic location, age, and gender.

To learn more:
Research Coordinators: Jennifer / Stephanie
Phone: 416-946-4501 x3297
clinicalgenet.research@gmail.com

Mount Sinai Hospital
Room 778D
600 University Avenue
Toronto, Ontario
M5G 1X5
Canada

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2 Replies:

  • I would be willing to help with studies if help is still needed. This is a very debilitating disease and it seems like so little is known. DNA Study for WG Patients Blood Donations Needed The goal of Dr. Katherine Siminovitch’s study: ‘Identification of Novel Wegener’s Granulomatosis Susceptibility Genes’ is to identify the genes that confer risk for disease. The study has already identified variants in three of the genes studied and determined them to be significantly associated with WG. While we are continuing to assess other gene variants for their relevance to WG, the study needs at least 250 more WG patients to donate samples to have sufficient data to develop results. It is very simple to participate in the study. Patients enroll in the study and have a blood sample drawn at their doctor’s office or laboratory and shipped to Dr. Siminovitch with the materials provided. If it is not convenient for you to have your blood drawn, we can send you a saliva kit – the saliva sample can be done in your own home. Identification of WG susceptibility genes will provide a promising avenue to the development of improved diagnostic and prognostic tests, as well as new targets for therapeutic management. All WG patients are eligible for the study, regardless of geographic location, age, and gender. To learn more:Research Coordinators: Jennifer / StephaniePhone: 416-946-4501 x3297clinicalgenet.research@gmail.com Mount Sinai HospitalRoom 778D600 University AvenueToronto, OntarioM5G 1X5 Canada
    BonnieCaldwell 1 Replies
    • February 12, 2010
    • 06:35 AM
    • 0
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  • I would be willing to help with studies if help is still needed. This is a very debilitating disease and it seems like so little is known.Hi Bonnie, Thank you for your post and willingness to participate in our study. Please email me at clinicalgenet.research@gmail.com so I can provide you with more information about our genetic study and what participation entails. Many thanks!
    clinical genetics 2 Replies
    • February 16, 2010
    • 06:34 PM
    • 0
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