Discussions By Condition: Immune conditions

autoimmune urticaria

Posted In: Immune conditions 1 Replies
  • Posted By: SRedekop
  • June 30, 2007
  • 01:14 AM

:confused: I need help!!! My daughter, 17, has been diagnosed with autoimmune urticaria. She was postive on the skin ****k test and her igE (?) levels were through the roof. This diagnosis happened summer 2005. We tried inhibitors first, reactine, prednisone and the like. Not effective. Next we did IVIG therapy. This was done every 3wks, and she had the migraine symptoms, missing school for 3days every 3 weeks. This was discontinued as it was becoming less effective as time went on. Started with every 4-5 weeks, when done she had the hives after 2 1/2 week doing the treatment every 3 weeks. Christmas 2005 we heard from a Dr in Hamburg, Germany who recommened Hyroxychloriquine. This to date has been exceptional! The problem now is she is the "one in a million" type that is having retinal damage from the medication. We were told yesterday she must discontinue this medication or will be losing her central and perifferal vision. :( The doctors here admittedly dont know where to go with her, and I know her quality of life without meds is terrible. She was head to toe hives, even with them internally.
I have just heard of some kind of plasma transfusions, and the use of some kind of cancer drugs. Has anyone experienced the use of these for this immune problem? Any help, suggestions, referrals would be so greatly appreciated.

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  • I know where you are coming from. Although my condition is not nearly as severe as it was when I was younger, I can relate. I have been continually reading through medical journals for the last 10 years trying to find some sort of therapy and hopefully a cure. It might be here. There is a new development in autoimmunity therapy, maybe a cure for some people. Below is a brief description of how it works. Their primary focus is for MS because its probably the most widespread. Here is the link to the company's web page. http://www.accentia.net/The therapy is called Revimmune. Revimmune uses an approved drug in a new patent-pending method to eliminate autoimmunity. Revimmune covers all of the estimated 80 autoimmune diseases that are currently recognized.In clinical studies for the lead indication of multiple sclerosis (MS), Revimmune improves function in most patients and stops progression in over 90% of cases refractory to standard therapies. Accentia Biopharmaceuticals, Inc. (NASDAQ: ABPI) has acquired the exclusive worldwide rights for Revimmune™, a patent-pending pharmaceutical treatment in late-stage development for a variety of autoimmune diseases. The in-license advances the Company's strategy of acquiring late stage drug candidates that can benefit from the 505(b)(2) regulatory pathway. Revimmune uses an ultra-high intensity, short-course of an intravenous formulation of an approved drug (cyclophosphamide), in a new patent-pending method to "reboot" a patient's immune system, thereby eliminating the autoimmunity, whereas current therapies including oral cyclophosphamide are used chronically to try to suppress the inflammation of autoimmunity. Based on long-term follow-up showing complete remissions, there is substantial evidence that Revimmune has the potential to cure cases of severe refractory autoimmune diseases such as aplastic anemia and myasthenia gravis.
    Anonymous 42789 Replies
    • August 23, 2007
    • 02:56 PM
    • 0
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