I have Primary Immunodeficiency Disease. I receive introvenous immunuglobulin therapy treatment every 3 weeks. My weakness is upper respiratory infections URIs-sinus infections, bronchitis, pneumonia, strept, etc. Treatment has helped tremendously. I continue to get sick but not as severe or as frequent. Since receiving treament I much more prone to GI issues-gas, bloating and stomach viruses.The immunologist just tells me that they dont know why but some patients begin to get frequent GI trouble once they start treatments. ??? Anyway, When I do get a URI it seems to be preceeded every time by the following symptoms: yellow stool, abdominal pain, nausea, sour stomach, and pain after a bowel movement that can make me double over and increased nausea after the bowel. Two days after these symptoms I will get my ususal sinus infection that then goes into bronchitis etc. So, what the heck is causing these freakish GI symptoms and how do they relate to URIs?