38 y/o female G-3, P-2 ages 4 and 8
Problem most noted 2 years ago
Episodic symptoms of: Severe fatigue, muscle weakness most pronounced in R upper thigh and knee, migratory joint pain, migratory muscle pain, memory problems, raynauds phen in R index finger only, malaise, bladder "muscle weakness" as in having to force urine out, constipation, dizziness, hot flashes.
Episodes becoming more frequent at least weekly, lasting 2-10 days at a time. Increasing prednisone relieves symptoms immediately. 10 mg daily keeps symptoms under control. Symptoms are exacerbated by physical activity, mental stress, and mostly by heat, (even a hot shower) Ex: A 2 hour shopping spree can put me in bed for 2-3 days. I cannot take a warm shower and continue with getting ready b/c I have to lie down. I have started taking my showers at night only so I can go to bed afterwards.
Cymbalta 60mg/day- muscle pain is not tolerable without it
gabapentin 200mg TID " "
Plaquenil 200mg BID- muscle pain, raynauds and memory problems get much worse if I forget or try to stop taking
Prednisone 10mg daily to keep symptoms under best control. Trying to taper off now at 7mg.
Vit D 50,000 units weekly
I have had extensive labs at multiple local hospitals, a university teaching hospital, and most recently at a prominent diagnostic hospital with the only interesting results being ANA of 6.8, CRP of 15.9, neg for sclero, sjogrens, lupus etc...
Neuro checked out OK, Cardiac OK except for concentric remodeling of L ventricle (?), Coags OK, MRI of brain neg x3
I cannot get a committed dx from any of my 3 rheumatologists, I get waste basket guesses only. (undiff. connective tissue disease, fibro, CFS)
I have lost my full time job, about to loose my part time job, I cannot take care of my children, my home or my husband properly and I am on the verge of a divorce due to this. Please help me if you can this is ruining my life.
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