Discussions By Condition: I cannot get a diagnosis.

Recurring digestive problems, antibodies, RUQ abdominal pain..

Posted In: I cannot get a diagnosis. 0 Replies
  • Posted By: runandonly
  • January 3, 2008
  • 00:50 PM

Ok, here is my story. I am a 22yr old female and since early August have been experiencing 'flare-ups' with these same symptoms: right upper quadrant pain and feeling of fullness/inflammation over the RUQ, sharper pain after eating, loss of appetite. When I first experienced symptoms they lasted only a day or two, but now each episode lasts about a week- during which I will have persistant RUQ pain. It is hard to describe the pain, but it is like a dull, constant throbbing with sharper pains every now and then. I feel the pain is exacerbated by stress. No changes in bowels with the symptoms.

I have had so many blood tests and such, yet still no diagnosis. My liver panels show ALT, AST, albumin right on the upper limit. Alkaline phosphatate is normal. The concerning tests were that I also have high Antinuclear Antibodies ANA (1:64) and Antimitochondrial antibodies AMA (1:95). After seeing these results, Dr. was sure it was Primary biliary Cirrhosis or autoimmune hepatitis. I had a liver biopsy done and just found out it came back NEGATIVE- no evidence of either disease or inflammation, etc. I have also had an ultrasound done of the RUQ, which came back normal- no evidence of gall stones or anything.

I am just at a loss here. The flare ups are becoming more painful when they occur (about 2x/month). Since August I have lost about 20lbs, which puts me at a very, very low BMI. THe loss of appetite and trouble eating from the symptoms don't help with that, either. Does anyone have any insight? I am going back for more tests (more in depth tests for celiac, dr may also suspect sphincter of oddi dysfunction?). This can't all be in my head!

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