Discussions By Condition: I cannot get a diagnosis.

Progressive Macular Hypomelanosis

Posted In: I cannot get a diagnosis. 8 Replies
  • Posted By: war_zone
  • May 27, 2007
  • 03:12 PM

hello ppl,

has anyone heard before of this skin condition? It creates very ugly white spots ard your stomach and back area(trunk area) and spreads upwards to ard your shoulders... my doctors have been classifying this as a new condition(which i realised too after research) and thus they have not been very helpful when it comes to offering treatment.

So far, i been using lotions on my skin(acne lotion to be exact, as its the same acne bacteria that is causing this problem)...and my doc has suggested that i go for shining(which is basically UVB or tanning in simpler terms) to bring the skin back to its normal colour. But he himself cant guarantee results...

arg i feel so sad and down...its really making my life upside down...cant really go out to do swimming and stuff..haiz.

hope someone out there can shed some light on this issue... many thanks

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8 Replies:

  • I went to the dermatologist today. and i was diagnosed with this skin disease. i was giving about three to four different things. two was prescribed for outward on the skin and i think one is to be digested in tablet form. i would of given you the details but honestly cannot make out a word. these doctors dont write too legible. I understand how you feel emotionally and how it has affected your lifestyle. I have had this throughout my teenage yrs and I am now 29yrs old. Could never face wearing a bath suit without wondering what people would say about my skin. My advice to you is not to extract your self from outdoor activities because of this condition. there are bathing suits that hide majority of affected areas. however, follow your dermatologists suggestions. I am trying out the solutions given for now and I have to see him back in a months time. If you want take my email address and we can support each other through this skin problem...however it should not change the person who you are as beauty is more than skin deep. If you have friends they should judge you not for your skin problems but for your personality..Hope you feel betterone lovetrinniki@hotmail.com
    Anonymous 42789 Replies Flag this Response
  • I have alrealdy been in your situation and for this reason I can understand you very well. But now, thanks God, I am extremely happy because I was successful with the following treatment (the therapy lasted 14 weeks). I recommend you to get this article and talk about it with a doctor. Good luck!!!http://linkinghub.elsevier.com/retrieve/pii/S0190962206008255Benzoyl peroxide/clindamycin/UVA is more effective than fluticasone/UVA in progressive macular hypomelanosis: A randomized studyJournal of the American Academy of Dermatology, Volume 55, Issue 5, Pages 836-843G. Relyveld, M. Kingswijk, J. Reitsma, H. Menke, J. Bos, W. WesterhofAbstractBackgroundThere is no effective treatment for progressive macular hypomelanosis. Recent findings indicate that Propionibacterium acnes may play a role in the pathogenesis.ObjectivesWe sought to compare the effectiveness of antimicrobial therapy with anti-inflammatory therapy in patients with progressive macular hypomelanosis.MethodsA total of 45 patients were randomized to a within-patient left-right comparison study of benzoyl peroxide 5% hydrogel/clindamycin 1% lotion in combination with UVA irradiation versus fluticasone 0.05% cream in combination with UVA irradiation. Repigmentation was determined by photometric measurements of changes in skin color and by patient and dermatologist assessment using before and after photographs.ResultsBenzoyl peroxide 5% hydrogel, clindamycin 1% lotion, and UVA led to better repigmentation than fluticasone 0.05% cream in combination with UVA irradiation in all measurements. (Photometric measurements P = .007, patient assessment P LimitationsThere was difficult objective color measurement. Therefore, subjective assessment has important additional value. Right-left comparisons have certain inherent limitations.ConclusionAntimicrobial therapy in conjunction with light was more effective in repigmentation in patients with progressive macular hypomelanosis than a combination of anti-inflammatory therapy and light.
    Anonymous 42789 Replies
    • January 12, 2010
    • 02:01 AM
    • 0
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  • The best solution is the ultra-violet or as mentioned tanning treatment, also known, if i remember correctly as -Psoralen and Ultraviolet A light (PUVA) treatment.It's a machine that you stand inside for a few minutes, 3 times a week for as long as you pigements clear out- which depends on how many times you doctor suggests.My pigements where not a lot, so I only had to go to 20 sessions, but I tired it and all was gone.But the problem with this was that by the next year they appeared again, so you have to do this process every year- depending on your doctor's suggestion.Another option is getting an actual tan, at the beach, but not too much since we all know too much sun is not good for you.Good luck...
    Anonymous 42789 Replies
    • November 9, 2010
    • 04:02 PM
    • 0
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  • Hi All, I have been diagnosed with this disease, and i am applying a cream which is called Nizorol, by my dematologist. She says its very successful, and it would ake about three months. I believe it contains benzoyl peroxide etc. She says she gets this quite often, and it can be cured. I can;t wait for my skin colour to return.I am 26years old, and i am a female. I have had it for the past five years, and i just ignored.
    Anonymous 42789 Replies Flag this Response
  • I've had this skin issue since I was about 8 years old. It started in my upper back and wasn't too noticeable so never really gave it a second thought. When I was about 28 years old, it just blossomed radically on my lower back and stomach. It never seemed to cause any problems except embarrassment and self consciousness but then I started getting concerned that it was spreading and so quickly. I've seen so many doctors that just gave me wrong information and made me spend money on creams that never did anything. Been doing a lot of my own research and finally found a skin specialist that diagnosed it right. She suggested the Benzoyl treatment and light treatment. Never did the light treatment and tried the Benzoyl which made my skin break out in major hives. I am going to give the tanning, benzoyl and clindamycin a try and see how it goes....
    Anonymous 42789 Replies Flag this Response
  • Im 19 and ive lived with this so long, its was all over my abdomen and a little on my upper leg. i never thought it'd get better, but thankfully it did. I saw a derm in Trinidad who correctly diagnosed me with PMH instead of Tinea. I literally cried when she said she could help me, all she did was look at it and knew what it was. (It is a common skin problem in the Caribbean) Its been 3 months an the meds that im on are working. Its not completely gone but its not noticeable unless you are close and looking for it. The doc's name is Dr.KB Maharaj, you can google her, i dont know whats in the medication she prescribes because it her own mix. She also had me on these pills when i started but my body didnt agree, the cream alone works tho, it just made the process take longer. Anyway, i hope this helps others.
    Anonymous 42789 Replies
    • August 19, 2011
    • 05:16 AM
    • 0
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  • After visiting 4 different dermatologists, I was diagnosed with Progressive Macular Hypomelanosis (PMH). Because PMH is fairly new and unknown, doctors thought I had Tinea Versicolor, which is a common fungal growth, and of course, the treatment had no effect on my whatsoever. I was so relived to finally know what I have... and that there is treatment for it! I understand your frustration about not showing your skin all too well. I've had problems with acne on my back since a teenager, and now in my late 20's PMH! I've never been able to sport a short haircut so I can use my hair to cover the rare instances when I have to wear a swimsuit or backless top! Stay positive, everyone! My doctor, a top expert in pigmentation problems (if you're in Southern California, I highly recommend her: Dr. Pearl E. Grimes), says she has seen very promising results with a combination of topical creams and light treatments. I'm just beginning my regimen of topical 1% clindamycin and 5% benzoyl peroxide and sunlight (no UV treatments for me yet). IF YOU'RE USING THIS TOPICAL TREATMENT, COULD YOU PLEASE GIVE ME YOUR FEEDBACK? Is it working? How long until you noticed repigmentation? Also, my doctor prescribed DUAC®, which is expensive and not covered by my insurance. Anyone using a generic version that is working great?Thank you in advance for your help... Good luck to everyone!
    Anonymous 42789 Replies
    • August 19, 2011
    • 06:44 AM
    • 0
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  • Hello ^^I've had PMH for past 5-6 yrs now..I live in oklahoma, and it seems like no dermatologist here even knows what PMH is..I want to get the UV light treatment but I don't even know which dermatology offers it.. does anyone know a good PMH derm in Oklahooma??and where do you guys get clindamycin 1% topical ointment, do you need a prescription for it?thanks so much!!!! ^^
    missno89 1 Replies
    • October 24, 2011
    • 02:07 AM
    • 0
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