Discussions By Condition: I cannot get a diagnosis.

Pretty severe itchy rash after Amoxicillin reaction

Posted In: I cannot get a diagnosis. 119 Replies
  • Posted By: Anonymous
  • June 2, 2007
  • 09:26 AM

Title says it all.
I was to take Amoxicillin for 10 days (prescription by dentist for tooth problem), on day 7 I woke up with a rash around upper torso. By the next day, it had spread full-body except for my head. The rash was spotted with big pink spots that were so thick in places it just covered all my skin.
At this point there actually was no itch, neither did the rash even hurt, felt more embarrassing then anything.
And of course I stopped taking Amox as soon as I saw the rash.

Now I've had the rash since Tuesday morning, it is now Saturday around 2:14am, I can't sleep, the itching is killing me slowly but surely. The rash itself is actually leaving, it is going away in the same pattern it came. Now the rash is really only visible from my knees down.

I have been taking cold showers and not going in the sun so as not to upset it. I have a regular lotion which helps "dry, itchy skin". I also have Califlora Gel as well as Gold Bond medicated anti-itch cream. None of these things are cutting the itching back at this point, it is driving me insane! It feels like pins and needles, I am compelled to at least touch the spot that itches, I am trying not to actually scratch.

The main problem areas are around my joints, elbows and knees. Moreso now at the knees since that is where the rash is worst. I tried sleeping in cotton full length jammies, tried bare-legged, tried putting a fan on my legs to keep cool. I even rubbed Aloevera juice on it but it will not stop bugging me. As of now I've got 15 layers of lotions on it and I can't put any more!

I'm at wits end, if this itching doesn't stop, I can't do anything! Help! What works?

Thanks a ton!

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  • Hi there,I know what your going through. My daughter had an earache June 16 2009, and i took her to the doctor that same afternoon. and she was prescribed amoxicillin. the next day we saw small rash, at first we thought it was just a bug bite but it was getting worst. I took her back to the doctor and they told her to try Zyrtec and that did not work either. I did alot of researching myself on the internet and tons of reading how to help her with her rash, i tried aloe and at first it looks like it was helping but the rash was the same, the the itch was not as bad. Then I tried the ''BAG BALM" it is used for healing blisters for Gymnast as my daughter is a gymnast. I would put bag blam on her rash then wrap bandaid on it. I kept doing that for 2 days straight and i started to see a difference. the rash that was on her chest was disappearing, it was 7 rash total on her chest and now its only 2 and i see its healing. oh before i forget, she was taking Benadryl also once in the morning and once again before bed. I give her 3tsp each time. It help her. I still did an appointment to her doctor today and saw her doctor and told her what i have been doing, but he know about amoxicillin could cause rashes and after i told him what i had tried, he prescribed my daughter "HYDROXYZINE" 10mg/5ml SYRUP....and "DESOXIMETASONE 0.05% CREAM 15GM.i gave it to her at 6pm because i knew she was going to bed at 8 pm and wanted to see if the medicine affects her at all like sleepy or etc....and she did not, like she does not feel sleepy as well when she takes benadryl. Anyways, after i gave her 1 1/2 tsp of the syrup medicine, i applied the cream on her rash, and after 1 hour, i checked up on her rash and i right away saw the difference. she is now sleeping, and i will check again tom. and I'm crossing my fingers that the medicine will work this time and fast, if not I know the "BAG BALM" works even tho it took couple of days for slowly disappearing its working. Its a green can container that you can get from walgreens pharmacy. Its up to you if you want to try it, just letting you know it works for my daughter who has rashes on her arms, chest, legs. email me badwahine@gmail.com if you want to know about her result tom. morning just incase i don't find this site to tell you. Good Luck and I will pray for your kid.
    Anonymous 42789 Replies Flag this Response
  • Wow. Day 8 of amoxicillin treatment for an inflamed tooth. Had a root canal 2 days ago, and while my tooth feels great now my skin is covered in an itchy rash. Nice informative thread. At least it isn't chicken pox. Kinda looked like that at first except for the massive concentration on my upper torso and shoulders. This really sucks. I'm gonna go look for some sandpaper sheets.
    Anonymous 42789 Replies Flag this Response
  • I was prescribed amoxicillin for a tooth that had to be pulled. I was on amoxicillin for 8 days with no reaction. On the eighth day I woke up and my inner/upper thighs had hives. As the day progressed I developed hives on my elbows armpits and the sides of my torso. I went to the ER and the doc told me to stop takin the amoxicillin, and gave me prednisone, benadryl, and famodritne* sp. I have been off the amoxicillin for 3 days and the hives come and go not to mention my hands and feet swell and itch and my face now has hives occasionally. Does anyone know how long these hives/rash will last after I have stopped the amoxicillin???? Thanks a reply would be awesome!!!
    Anonymous 42789 Replies
    • August 16, 2009
    • 08:09 AM
    • 0
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  • Ive been trying to research the "amoxicillion rash" thjing as well. I have an 11 month old son, who had a febrile seizure due to an ear infection he had. He was tugging on ears and asked Dr., she checked and said they looked fine. NOt even 2 weeks later he had the seizure, due to 104 fever from the infection. They prescribed him amoxicillion as well. After three days of being on itTry taking some benedryl - it will help with the itching and reduce the hives.However, you should have also informed your doctor about the reaction.Contrary to what sports.chick.19 says - you ARE allergic to amoxicillin. As is sports.chick. That is the whole definition of an allergic reaction - you respond to the medication - hives, rash, difficulty breathing. If you or sports chick takes it again, you could have a more serious reaction (anaphlaxis) and die. You need to tell all providers in the future about htis reaction and that you are allergic to this drug .I am a NP
    Anonymous 42789 Replies
    • August 17, 2009
    • 02:21 AM
    • 0
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  • I have never replied to one of these posts, but I have to share my own experience.I am in my 40s now, but when I was in my early 20s I got a bad sore throat and swelling around my sinuses. My doctor diagnosed a sinus infection and put me on amoxicillan (I forget the dose, but it was in line for an adult). After day 10 I broke out in a rash that spread all over me -- no kidding, head to toe, scalp and eyelids. Even the palms of my hands were bright red. In addition, I had a lot of trouble swallowing even water. I gained 10 pounds in 3 days and every inch of me was one joined swollen hive.My doctor examined me and he frankly had no idea what the problem was. I was sent to a hospital a few days later where about 5 or 6 doctors came to look at the freak patient. Finally, I was diagnosed as having an allergic reaction to amoxicillan. They gave me a blood test that confirmed I had mono and strep. Apparently, in about 90% of the cases where the epstein-barr virus or mono is present, this reaction can occur. Since the virus stays in your body forever (this is what I was told), I will always be allergic to this medication. I also have reactions to ampicillan, keflex and other medications from the penicillan family. This was discovered after I took these medications for other minor infections throughout my adulthood. The telltale sign for me for a medication/allergic reaction is the itchy palms. I take benedryl to squash the reaction and tell my doctor.My advice, especially for people with kids who cannot tell their parents how they feel, is to have your doctor or your child's doctor test for strep and mono. Both are very easy to catch and often (especially mono) will be overlooked as a diagnosis. After the horrible experience I first described, be advises (to people who are going through this now) that between getting the rash and getting rid of it enough so I could go back to work, was one month. Yes, I missed 4 weeks of work and was 10 pounds thinner than before I got sick. Good luck. Hope this info helps.
    Anonymous 42789 Replies
    • September 4, 2009
    • 01:22 AM
    • 0
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  • listen take benedryl - it helped me immensely ! this is the second time I've had a horrible allergic reaction to either penicilin or an antiobiotic (I seem to be allergic to both!) - maybe my body has built up some tolerance because this time was not quite as horrid as my last break out - but the benedryl has helped and DRINK tons of liquids - my pharmacist said it is excreted in the urine and you just gotta get the stuff out of your systemhope that helps - it's no fun.... and meditation helps - just try not to get frustrated - although I know that is hard when the rash is itchy and painful - but getting stressed will only make it worseI was to take Amoxicillin for 10 days (prescription by dentist for tooth problem), on day 7 I woke up with a rash around upper torso. By the next day, it had spread full-body except for my head. The rash was spotted with big pink spots that were so thick in places it just covered all my skin.At this point there actually was no itch, neither did the rash even hurt, felt more embarrassing then anything.And of course I stopped taking Amox as soon as I saw the rash.Now I've had the rash since Tuesday morning, it is now Saturday around 2:14am, I can't sleep, the itching is killing me slowly but surely. The rash itself is actually leaving, it is going away in the same pattern it came. Now the rash is really only visible from my knees down.I have been taking cold showers and not going in the sun so as not to upset it. I have a regular lotion which helps "dry, itchy skin". I also have Califlora Gel as well as Gold Bond medicated anti-itch cream. None of these things are cutting the itching back at this point, it is driving me insane! It feels like pins and needles, I am compelled to at least touch the spot that itches, I am trying not to actually scratch.The main problem areas are around my joints, elbows and knees. Moreso now at the knees since that is where the rash is worst. I tried sleeping in cotton full length jammies, tried bare-legged, tried putting a fan on my legs to keep cool. I even rubbed Aloevera juice on it but it will not stop bugging me. As of now I've got 15 layers of lotions on it and I can't put any more!I'm at wits end, if this itching doesn't stop, I can't do anything! Help! What works?Thanks a ton!
    Anonymous 42789 Replies
    • September 8, 2009
    • 04:26 PM
    • 0
    Flag this Response
  • I recently got an eye procedure done - it was scrapping of fat tissue buildup under the eye lid. After that the Dr priscribed Amoxicillin 500 mg three time a day of 7 days. On the morning of day 5, I was covered with a red rash all over my body and some parts were very itchy. I stopped the antibiotic and the Dr told me to take Benidryl 25 mg every 6 hrs. After 4 days of Benidryl the rash was nearly gone but I got extreme itching on my feet and palms of my hands. For the last 2 nights I have been awake, itching till 5 am when I fall asleep and get up again at 9 am with the same itch. I also noticed decrease in urine and swelling on my feet. Due to it being weekend, have not been able to speak to my Dr but I have stopped taking Benydril. Maybe its the Benydril that is keeping me awake. My urine passing has now improved but would like to know if I can use something else to replace the Benydril to stop the itching. I just tried keeping a bag of ice on my feet for a while and that helped a lot to stop the itching but I think it will not be for long. Thanks for your input.
    Anonymous 42789 Replies
    • September 13, 2009
    • 10:15 PM
    • 0
    Flag this Response
  • Took Amoxicillin for 2 days and on day 3 I had a little rash on my thigh. My doctor said to take Benedryl. I did. The next night the rash was all over my inner thighs and was now in splotches on the sides of my torso, shoulders and arms. I went to the ER where they prescribed Prednisone and Benedryl. Now, tonight, I am covered in this itchy splotchy mess ALL over my body. It's now starting to develop on my face (under my left eye) and my hands. Without a shirt on in the mirror under the bathroom light - I look horrendous! My girlfriend has a look on her face that resembles sympathy, but has an underlying look of fright. I no longer ask her opinion on if this rash is getting better, and I'm almost sure this rash will eventually kill me.I have no fever and no pain (other than the itching), but I feel sickly nontheless. Not much of an appetite either. The Prednisone and benedryl definitely help the itch but the rash remains. I don't understand why this rash is getting so out-of-control and none of the doctors are saying it's due to the Amoxicillin. By the way, the illness that original merited a round of penicillin is completely gone. Next time I think I'll just tough-out my sickness meds free.
    Anonymous 42789 Replies
    • October 2, 2009
    • 07:05 AM
    • 0
    Flag this Response
  • *Follow-up from 10/02/09*Ok. Finally an answer after 2 blood tests and 5 doctors. A doctor told me last night that I have mono and that when taking amoxicillin with mono (and/or Epstein-Barr syndrome) causes this type of reaction. He said hives shouldn't last more than 7-10 days. However, all last night I had a HUGE flare-up and I took more Prednisone (steroid) and Benedryl 25mg but my legs and feet were unaffected. Horrible burning and itching from thighs down with big welts! This morning though I haven't a single blemish on my body. No itching or welting. Just the places where I broke my skin scratching. I am hoping the worst is over and this rash/affliction just wanted to "go out with a bang". Now I fear that in the future, every time I have an itch somewhere on my body, I will want to do a full-body inspection of my skin to keep my mind at ease. I WILL NEVER AGAIN TAKE ANTIBIOTICS! I wish everyone who experiences this all the best. I wouldn't wish this on anyone. OK, maybe just 1 or 2 people.
    Anonymous 42789 Replies
    • October 4, 2009
    • 06:23 PM
    • 0
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  • 7 days into a amoxicillin Rx and my rash started. I was gardening out in the sun and thought there were bugs biting me. That night I thought I just been attacked by fleas or chiggers. Now I know for certain it was the amoxicillin. I'm into the first 24 hours of this and I don't know how people work while on benedryl. It makes me so sleepy. Hopefully, drinking tons of water and taking a probiotic will fight off this fast. I am a little concerned with some of the posts stating it takes months and one case over 3 years of symptoms. I do notice a deep pain almost in my left femur which I attribute to the amoxicillin.
    Anonymous 42789 Replies
    • October 16, 2009
    • 00:27 AM
    • 0
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  • Try taking some benedryl - it will help with the itching and reduce the hives.However, you should have also informed your doctor about the reaction.Contrary to what sports.chick.19 says - you ARE allergic to amoxicillin. As is sports.chick. That is the whole definition of an allergic reaction - you respond to the medication - hives, rash, difficulty breathing. If you or sports chick takes it again, you could have a more serious reaction (anaphlaxis) and die. You need to tell all providers in the future about htis reaction and that you are allergic to this drug .I am a NP-Actually you can look on wikepedia and it states these rashes 7-8 days after taking amox. is a non-allergic reaction and is natural in kids and some adults. I'm experiencing this right now and my doctor told me to continue taking the pills and to call if something gets worse otherwise its common and fine they get these sorts of calls a lot. Mine I noticed after waking up and it covered my face and torse. Its mildly itchy on my face only and otherwise I feel comfortable, today atleast. It looks pretty rediculous though.
    Anonymous 42789 Replies
    • October 17, 2009
    • 10:48 PM
    • 0
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  • My 14 month old son had the same reaction starting on day 9 of his Amoxicillan Rx - he was on it for an ear infection. He was initially started on Prednisolone for the allergy, but now the MD has him on children's liquid Zyrtec qday. We are now on day 7 of the rash that comes & goes varying from light redddish pink blotches to welts & purplish splotches. It's weird the way the spots will come & go in minutes, but they're always there - somewhere. He's had the rash all over his body - mostly on his belly & armpits, but even on the palms of his hands, the soles of his feet, & btwn the toes too! I'm hoping it won't last much longer - but I'm anticipating at least another week of this!
    Anonymous 42789 Replies
    • October 27, 2009
    • 09:28 PM
    • 0
    Flag this Response
  • Good morning to whomever. I just received a frantic call from my 6 year old sons mother. It seems our boy, Cameron, has a rash all over his body, red bumps similiar to measles. So I immediately went to my laptop to see what I could find, and here I am. As I'm learning here, it sounds like a reaction from his medicine, amoxicillion. His doctor was called and he thought the same and wants to see Cameron this morning. So I guess I'm trying to get some info on what to expect and how to comfort my little guy since he will be wiyh me the next few days. I'm concerned about the itching I'm reading about. Any GOOD remedies that might help my son deal with the itching? Thanks Jim.
    Anonymous 42789 Replies
    • October 29, 2009
    • 00:56 PM
    • 0
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  • The NP is incorrect. This is a delayed hypersensitivity reaction that commonly occurs with amoxicillin. If a rash takes longer than 72 hours to appear it is not a true allergy. However, a primary care provider should be contacted for reactions like this so it can be properly documented in your medical records and so you can get medical advice frosomeone who actually is trained to make that diagnosis by asking you appropriate questions about symptoms, time of onset and other precipitating factors.Try taking some benedryl - it will help with the itching and reduce the hives.However, you should have also informed your doctor about the reaction.Contrary to what sports.chick.19 says - you ARE allergic to amoxicillin. As is sports.chick. That is the whole definition of an allergic reaction - you respond to the medication - hives, rash, difficulty breathing. If you or sports chick takes it again, you could have a more serious reaction (anaphlaxis) and die. You need to tell all providers in the future about htis reaction and that you are allergic to this drug .I am a NP
    Anonymous 42789 Replies
    • November 16, 2009
    • 10:57 AM
    • 0
    Flag this Response
  • This statement is not supported by clinical evidence. The effect of antibiotics on birth control is not clear, it would appear that certain antibiotics have affected a small number of patients on concomitant birth control. This is the reason a back up method is recommended. Antibiotics completely ruin birth control effectiveness...just let your daughter know this will happen every time she takes any antibiotic so she uses a back up birth control to avoid an unplanned pregnancy...often women don't know this and their docs don't tell them... Also, a steroid combined with the antibiotic use will impair her immune system, and can lead her to have candida overload as well. Please have her take a good quality PROBIOTIC to help rebuild her immune system and avoid candida overload. This is very safe and will keep her in balance. Glad she is doing better.:) Best wishesDOM
    Anonymous 42789 Replies
    • November 16, 2009
    • 11:02 AM
    • 0
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  • I got Amoxicillin against a persistent ear infection after the first antibioticum didn't help at all. The second day, my hands and soles began to prickle...I didn't think much of it, because I have never been allergic to anything in my whole life. The third day, the prickle got worst. The fourth day I went to the doctor...by now, my feet were red, as were my hands and especially my wrists. The doctor gave me Cetrizin and ordered me to stop taking the medicament and stick with the ear drops. This was a Friday...I went back to the doctor at Monday. By then, I had a rash from my feet up to my decoltee, my hand were swollen, my joints hurt and I felt very squeezy...I actually hat dry heaves this morning...the Cetirizin didn't help at all! The doctor consulted with a collegue and prescirbed me cortisone. Well, the rash didn't spread anymore (so luckly, my face got spared)...and my hands aren't swollen anymore either, and I feel not sick in the stomach anymore. But now the itch is killing me! It is wednesday, and I feel like I have gotten a bad sunburn and rolled myself in nettles afterwards! I woke up the last two mornings from myself scratching over my arms. I tried to keep the skin cool....doesn't help at all (it actually makes it worse by now). Fenistil helped the very first days, but by now, it only makes it worse, too! The only place I feel comfortable is lying in the bath, in lukewarm water...but I hardly can stay there all day. Has anybody any idea what I can do against the itch? (Nothing which could interfere with the cortisone, just some creme or so). I searched the whole internet, but nobody seems to have a good remedy for this.
    Anonymous 42789 Replies
    • November 25, 2009
    • 08:22 AM
    • 0
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  • The 5 best treatments in this world are spiritual cure, herbal therapy, natural health therapy, acupuncture and thermogenesis. They are safe, effective, leisureable and pleasurable. Title says it all.I was to take Amoxicillin for 10 days (prescription by dentist for tooth problem), on day 7 I woke up with a rash around upper torso. By the next day, it had spread full-body except for my head. The rash was spotted with big pink spots that were so thick in places it just covered all my skin.At this point there actually was no itch, neither did the rash even hurt, felt more embarrassing then anything.And of course I stopped taking Amox as soon as I saw the rash. Now I've had the rash since Tuesday morning, it is now Saturday around 2:14am, I can't sleep, the itching is killing me slowly but surely. The rash itself is actually leaving, it is going away in the same pattern it came. Now the rash is really only visible from my knees down. I have been taking cold showers and not going in the sun so as not to upset it. I have a regular lotion which helps "dry, itchy skin". I also have Califlora Gel as well as Gold Bond medicated anti-itch cream. None of these things are cutting the itching back at this point, it is driving me insane! It feels like pins and needles, I am compelled to at least touch the spot that itches, I am trying not to actually scratch. The main problem areas are around my joints, elbows and knees. Moreso now at the knees since that is where the rash is worst. I tried sleeping in cotton full length jammies, tried bare-legged, tried putting a fan on my legs to keep cool. I even rubbed Aloevera juice on it but it will not stop bugging me. As of now I've got 15 layers of lotions on it and I can't put any more! I'm at wits end, if this itching doesn't stop, I can't do anything! Help! What works? Thanks a ton!
    Heal Chronic Illness 18 Replies
    • November 26, 2009
    • 06:47 PM
    • 0
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  • I got a pretty severe rash on my thighs, neck and groin area, and now my stomach after taking antibiotix (azithromycin -Z-pak). This happened around day 7-8 after I was done with the medicine, was taking for bronchidus after the flu, possibly swine flu.This morning (like day 11 now) I woke up and it had spread to my face and eyes. My eyes were all puffy. At some point a few hours later I could not breathe. I was very short of breath and could barely swallow. I started to go to the urgent care, but there was a line and really felt like this thing was closing up my airways and throat. So I went to the Emergency Room.Long story short, the dr.'s took me right away and gave me a steroid IV of prednesone (or similar) and some benedryl. Oh, and an epi shot - epinephrine.This all helped me to breathe and calm down. I don't know if I'm over this, but I got the steroid meds to start taking tomorrow and I feel like the Dr.'s and nurses saved my life. It was not fun, I was, and am still, miserable with this rash all over my face, next and yes, even down "there". Itches like crazy, but the benedryl helps a bit with that.God bless any of you who get this rash, it is no fun and can be life threatening. I would say to go to the Dr. if you get this rash before you end up like me with it suffocating you from the inside.Oh, and I will never take antibiotics again unless I'm sure I'm going to die without them.
    Anonymous 42789 Replies
    • December 7, 2009
    • 07:29 AM
    • 0
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  • Scary stuff, huh? Here's what's happening to me!I came down with "something" in the early morning of Tuesday 2 weeks ago (day 1). Started as a cough. I toughed if out for 2 days and thought I was getting better. I had to leave work on Thursday (day 3) because I felt terrible. I thought I would get better by Monday after resting for 2 work days (Thursday and Friday) and the weekend (Saturday and Sunday). I work in Russia and have access to a work doctor. I blew him off every time he wanted to examine me.The following Monday (day 6), my cough (non productive) was worse and I felt like someone had beaten me with a baseball bat. I also developed a "wheezing" when I exhaled my lungs completely. I imagined that my lungs were slowly filling with fluid and my coughing was not producing anything. I couldn't see our doctor fast enough! The doctor showed up to my place, took my temperature (normal every time he checked it over the following 5 days in a row) and heard that my lungs were not working so well. We went to a local medical facility (scary!) and got an x-ray taken of my chest. It was "clean" (yay!). He then swabbed my mouth and nose for flu tests. The results would be ready the next day. He suspected that I had the flu and that maybe I had developed a bacterial infection in my lungs, which may have started the "wheezing". So, he prescribed Tamiflu for the possible flu and Amoxicillin for the possible bacterial infection.On Tuesday (day 7, day 2 of Amoxicillin), the flu results came back positive for H1N1. I couldn't tell if I had a rash, because my whole body felt "on fire" and noticing that my skin may be covered in a rash was the least of my worries. On Friday, (day 10, day 5 of Amoxicillin), I noticed that my wrists and knees had "red blotches". I took a cold shower and wondered what I may have eaten to cause the reaction. The shower helped and I thought the reaction was subsiding. So, I took the last dose of Tamiflu and the continued doses of Amoxicillin for that day. My rash worsened and that's when I figured the rash was here to stay.The next day, Saturday (day 11), I SMS'd the doctor to come see me and look at the rash that covered my wrists, knees and my torso area. He advised to stop the Amoxicillin and start taking Claritin. It's now Monday (day 13, day 3 after last Amoxicillin) and I still have the rash predominately visible on my wrists, knees and now feet and sprinkled over my arms and legs . I can't tell if I still have it on my torso or not. It may be gone, or I may be so blotchy that I look like I have a tan (I kinda like the way the way my torso looks, actually). I have no itching, but some times I can't sleep at night because my ankles and wrists "feel strange". The doctor gave me Suprastin (25mg) to try and releave the rash. It's not working either.I will try and update this after this rash get's cleared up. I already knew I was allergic to Penicillin from when I was in college (I was 21 y/o, I'm 41 y/o now). I even had the same type of skin reaction back then. Scared me very badly back then. My Mom even had to come babysit my spoiled butt. Now, not so scary. This too shall pass. The question is "when?". The H1N1 was way scarier than this skin rash will ever be.I figure the Amoxicillin rash will go away when I get all the Amoxicillin out of my system. I know it's still in the system by the smell when I have to use the toilet.
    Anonymous 42789 Replies
    • December 7, 2009
    • 01:33 PM
    • 0
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  • I am 68, male. Dentist prescribed AMOX for tooth extraction. No rash, but I swear these strong 10day antibiotics cause feelings of depression. It has happened at least 3 times that I have been on them. This time, 7 days after finishing AMOX, I developed pleurisy. I don't know, but suspect AMOX somehow weakens natural defenses to later infections.
    Anonymous 42789 Replies
    • December 7, 2009
    • 05:52 PM
    • 0
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