Discussions By Condition: I cannot get a diagnosis.

Persistant fever and cough

Posted In: I cannot get a diagnosis. 0 Replies
  • Posted By: rmmathur
  • October 2, 2009
  • 02:05 PM

I am 41 years female, married with 2 children.

I started having cough in early December 2008. I started having high fever (103 F) after 2 weeks. I took treatment antibiotics, Malaria, Urine infection. I was hospitalized in January 09 for 5 days. I received anti malarial, antibiotics and was discharged. I started having fever after a week, cough was persistent.
There was some urine infection, i took antibiotics and it cleared.

I have got chest X ray which is clear. Urine culture, VDRL, HIV 1 and 2, were negative.

TB Elisa

Mycobateria IgG serum 310
Mycobacteria IgM serum 0.51
Mycobacteria IgA serum 108

Angiotensin Coverting Enzyme, Serum 105 u/l

Anti nuclear AB-IFA, Hep 2, serum (14/2/09)

Antinuclear Antibodies Postive

Primary dilution 1 : 40

Primary intensity on IF 3+

ANA pattern Speckled

End point Titre 1: 640

I started with Tuberculosis drugs for a week and stopped as the fever and cough were still persistant.

I started treatment and Scleroderma 40 mg Prednisolone. and gradually come down to 5 mg

The fever and cough is still persistent.

I have got Chest ( Plain and Contract) CT scan. Which was normal and there were no major findings.

Latest tests results (25/9/09)

SGOT/AST 29.8 U/L

SGPT 24.1 u/l

Alkaline Phosphates 138 u/l

C- reactive protein 8.8 mg/L ( ref range< 5.01)


C 3 Complement Component 113 mg/dl

Anti-ds DNA anti body (elisa) 18.79 IU/mL

Antinuclear anitibody/ Factor, IFA; ANA/ANF, HEP-2

ANA: Negative

Cough is persistent and fever is occasional.

Please help with diagnosis

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