I am 41 years female, married with 2 children.
I started having cough in early December 2008. I started having high fever (103 F) after 2 weeks. I took treatment antibiotics, Malaria, Urine infection. I was hospitalized in January 09 for 5 days. I received anti malarial, antibiotics and was discharged. I started having fever after a week, cough was persistent.
There was some urine infection, i took antibiotics and it cleared.
I have got chest X ray which is clear. Urine culture, VDRL, HIV 1 and 2, were negative.
Mycobateria IgG serum 310
Mycobacteria IgM serum 0.51
Mycobacteria IgA serum 108
Angiotensin Coverting Enzyme, Serum 105 u/l
Anti nuclear AB-IFA, Hep 2, serum (14/2/09)
Antinuclear Antibodies Postive
Primary dilution 1 : 40
Primary intensity on IF 3+
ANA pattern Speckled
End point Titre 1: 640
I started with Tuberculosis drugs for a week and stopped as the fever and cough were still persistant.
I started treatment and Scleroderma 40 mg Prednisolone. and gradually come down to 5 mg
The fever and cough is still persistent.
I have got Chest ( Plain and Contract) CT scan. Which was normal and there were no major findings.
Latest tests results (25/9/09)
SGOT/AST 29.8 U/L
SGPT 24.1 u/l
Alkaline Phosphates 138 u/l
C- reactive protein 8.8 mg/L ( ref range< 5.01)
C 3 Complement Component 113 mg/dl
Anti-ds DNA anti body (elisa) 18.79 IU/mL
Antinuclear anitibody/ Factor, IFA; ANA/ANF, HEP-2
Cough is persistent and fever is occasional.
Please help with diagnosis