Discussions By Condition: I cannot get a diagnosis.

painful blisters and MS

Posted In: I cannot get a diagnosis. 5 Replies
  • Posted By: budgeot
  • December 29, 2007
  • 05:41 PM

My doctors do not know what the painful, and slightly itchy, deep blisters are on the sole and sides of my left foot.

I was diagnosed with MS (Multiple Sclerosis) in November 2007, having had some months of significant weakness on my left side - e.g. a noticeable limp and a left hand that will not 'clench' - and then suffered severe pain of my lower spine after a lumbar puncture on November 7th. That pain won't go away, and I have just been X-rayed to see if it is actually arthritis of my spine. .

I also had three large doses of intravenous steroids when I was in hospital, early November, but none before or since. No remission of my MS because of that, though.

Having these really painful, roughly-circular , blisters - they are a half centimeter to a centimeter across, purple in color... except for the oldest, which are turning yellowish in their centers... is not helping me walk. I do walk with a stick now, but this foot pain really does NOT help!

I am female, and have had arthritis in my right knee since I was 23 (I am now 52) with more recent arthritis in my elbows, wrists and fingers, and psoriasis of my scalp, ears, and elbows for many many years. Since a traffic accident in 2003 I have persistent whiplash pain in my right shoulder and also Paroxysmal Atrial Fibrillation which, because I have such low blood pressure, is not being treated but just noted.

I am worried that my MS may be 'damping out' some of the pain in my foot and most of the itchiness, as my third and fourth toes on my left foot are now completely numb. I worry that in trying to walk I might be causing more problems than not. My sister (48) has had similar blisters (we spoke on the phone) for about 8 months and is now on a very strong steroid. About to have daily UVA light therapy for them. On her advice I am treating them with petroleum jelly and wrapping them in sterile bandages though - unlike hers - they have not popped. Yet!

Advice, please!


Many thanks.

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5 Replies:

  • what do you think about the possibility of them being shingles? That would be consistent with having began after strong steroid treatment, being painful, unilateral, dermatomal, changing color and becoming slightly itchy... Maybe something to think about.
    fewd4thought 126 Replies
    • December 31, 2007
    • 09:06 AM
    • 0
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  • have it scraped and analyzed, it could be MRSA..
    Monsterlove 2921 Replies
    • December 31, 2007
    • 09:57 PM
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  • Thanks for reading and replying. I don't think these are shingles blisters (I had shingles decades ago but it was nothing like this). Also, as the blisters have not yet popped I don't think I can get them scraped. Today there are three large bright-to-dark red blisters very near the surface, looking as though they might puncture at any moment. Very painful even when I am resting, but super-sore if I try to walk on them.These are no longer circular/spherical, but have an irregular margin... almost star shaped. Others are smaller or not as near the surface, except the one on my heel (which I skinned off in an accident and is circular and fluid filled and now slightly tender and a little infected, but not enough for the doctor to want to do anything but watch what happens ). I have about a dozen large blisters on my left foot and heel and (thankfully) do not seem to be developing more. Also the small blisters on my fingers (loads of tiny blisters all over the edges nearest my thumbs) are less obvious than they were a week ago.With luck now I suppose I might not need to know what they are...best wishes and thanksCaroline
    budgeot 1 Replies
    • January 7, 2008
    • 06:23 PM
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  • Omg, I finally feel as though I have meet someone who is explaining my issue to a T! I also suffer from these painful irregular shapes blisters. They only seen to be on my left side which is also where I experience MS weakness. I do occasionally get them on my fingers and once on my elbow. They are there for a couple weeks and then they are gone. Shockingly I have received ZERO input from my neurologist or my primary... So I suffer through them until they go away. I have just ordered probiotic drops as I'm not sure if this can be "cured" via the gut. I'm all out of answers
    Anonymous 1 Replies Flag this Response
  • I have MS was diagnosed in 1998. I have been having the blisters also on the bottom and sides of my left foot since 2010 which is also my weak side. My PC Dr. Sent me to a dermatologist who in turn prescribed Triamcinolone Acetonide cream. Seems to help with clearing them up, but not from stopping them. Often wonder if it's not MS related.
    Anonymous 1 Replies Flag this Response
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