Help! My mother is a medical mystery right now. She just turned 54, and was very healthy up until this past Thanksgiving. She has a herniated disk in her neck, and it was bothering her at the time, then she ended up ill with headache, nausea, and vomiting for a few days. My dad brought her in to the clinic after several days of this, and they hydrated her then she went home. The following day she literally had to crawl out of bed, and went back to the clinic. Ended up in ICU!
Normal sodium is 135-145 and her's was 107. This was a critical level that could have caused her to have siezures, go in to a coma, or death.She just had mild confusionLab tests show that she definitely has SIADH Syndrome of innappropriatie diuretic hormone. Colonoscopy was normal, and full body scan showed nothing except a small mass on the lung and that her pituitary is flat. She was put on a fluid restriction of 1 quart of fluids a day, but sodium is checked every few weeks, and still is in the low 120's. She had a repeat scan of the chest after one month, and the mass had not changed.
She was referred to the Mayo clinic. Plan was to biopsy the mass on the lung, but was too small. She met with a thoracic surgeon, and it was decided to do surgery. She ended up having 1/4 of the left lower lobe of the lung removed, and it was mass was benign.
So, she has SIADH, and sodium remains low even with the fluid restriction, but they can's find the underlying cause. Plan is to try Demeclocycline, a medication that may help, and she will have the sodium checked every few weeks. She will also meet with endocrinology at the Mayo again in June.
Anyone ever hear of SIADH? Help! I hope to help her figure out what is wrong.
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