Discussions By Condition: I cannot get a diagnosis.

Mucousal hyperpigment/polyendo/autoimmune

Posted In: I cannot get a diagnosis. 0 Replies
  • Posted By: Anonymous
  • May 24, 2008
  • 08:23 PM

I have been to Mayo recently and I still do not have an explanation of why suddenly at 28 and very healthy and skinny and athletic I became very very ill. It started with rapidly progressing vitiligo and black mucousal hyperpigmentation in the groin area and a small spot under the tongue. My liver enzymes, ANA, were elevated and rising rapidly, I have and had then a lupuslike malar rash and rapidly progressing spinal stenosis, spondylitis, degeneration, and herniated disks. I developed severe grade three NASH.

I have been told it is allin my head--I guess that causes severe pigment problems:)! I was diagnosed with polyendo dysfunction type 2, I now have diabetes, hashis, severe NASH, adrenal insufficiency, and sjogrens syndrome. I have IBS now, diverticolosis throughout my colon and lost my reproductive organs due to severe polycystic ovary and endometriosis. I have lost my salivary glands and surrounding lymph nodes to benign hyperplasia and lymphocytic infiltration and chronic inflammatory cells. I also now have bouts of incontinence, low or high blood pressure, nausea and failure to digest food, occasional bleeds due to chronic inflammation of the bladder floor or duodenum. I have about forty urethral polyps and have had an adenoma removed from my colon.

No one can tell me why I am so rapidly deteriorating. My liver is stable now and my inflammatory markers and sjogrens is under control, with my ANA only mildly elevated.

I believe I have and have had Addisons disease due to the mucousal hyperpigmentation, since I can't find any other reason for it. I am desperately trying to be treated for that. I have had excessive rapid weight gain around the middle from hashis and possible cushings also, so they think I'm not skinny enough to be sick with Addisons. I do very well with steroid supplementation.

I'm dying, with no single diagnosis, and all these normally mild conditions are very severe in me. Any help would be appreciated. What can I do to get a good overall diagnosis?

Reply Flag this Discussion
Thanks! A moderator will review your post and it will be live within the next 24 hours.

Signs of a Psoriasis Flare

Know the five types of psoriasis and how to spot flares.

How Diabetes Medications Affect Your Appetite

Newer diabetes treatments can suppress appetite and aid weight loss.

What to Do For Dry Mouth

Try these tips to get your salivary glands back into action.

The Painkiller – Constipation Connection

Constipation is a common side effect of opioid and narcotic pain medicines.

9 Signs of Sensitive Skin

Is it sensitive skin or something else?