Discussions By Condition: I cannot get a diagnosis.

MTHFR and Factor V Leiden

Posted In: I cannot get a diagnosis. 2 Replies
  • Posted By: mlamb331
  • March 22, 2008
  • 10:02 PM

Hi,

I am 36 years old and 6 1/2 weeks pregnant with my first baby. I have 2 copies of MTHFR A1298C. My homocysteine level was 4.7 in Dec. 2007. I have been tested for Factor V Leiden and according to the results, it says that I am negative for the R506Q mutation, but that this does not rule out other mutations within the Factor V gene. What does that mean???

My fertility doctor has me taking 1 baby aspirin a day and also folamin (I'm not sure what the dosage is, but I take 2 peach-colored pills a day). My 2 questions are: 1. Do I need more testing for Factor V Leiden? 2. Are the pills I am taking now sufficient to help sustain this pregnancy or should I be taking lovenox or some other blood thinner?

I appreciate your help!

Reply Flag this Discussion

2 Replies:

  • You get a blood test for Leiden Factor V but there are many strains of leiden, that make the same problem happen, taking the little orange low dose aspirin is to prevent you from stroke, heart attack, or thrombosis. I have Leiden factor V(1 Copy), and Take the aspirin my self, it's a prevention, not a cure. http://en.wikipedia.org/wiki/Factor_V_LeidenFactor V Leiden causes blood clotting issues, which can cause Stroke, or Heart Attack by embolism. Embolism is where you have internal bleeding, and it clots up, then breaks off and travels around the body, for some it settles in their lungs, other time's it can travel and cause damage to the heart and brain. The Aspirin is an anti coagulant, Which helps your blood flow easily, with less likely hood of the embolism to occur. MTHFR and Factor V Leiden both cause still births and defects when you have the gene's.But I wonder can you have both gene's? I think I might get tested for MTHFR! and find out if I have it, and do more research to find out how the two gene's are similar.
    Anonymous 42789 Replies
    • September 14, 2010
    • 10:52 PM
    • 0
    Flag this Response
  • You get a blood test for Leiden Factor V but there are many strains of leiden, that make the same problem happen, taking the little orange low dose aspirin is to prevent you from stroke, heart attack, or thrombosis. I have Leiden factor V(1 Copy), and Take the aspirin my self, it's a prevention, not a cure. http://en.wikipedia.org/wiki/Factor_V_LeidenFactor V Leiden causes blood clotting issues, which can cause Stroke, or Heart Attack by embolism. Embolism is where you have internal bleeding, and it clots up, then breaks off and travels around the body, for some it settles in their lungs, other time's it can travel and cause damage to the heart and brain. The Aspirin is an anti coagulant, Which helps your blood flow easily, with less likely hood of the embolism to occur. MTHFR and Factor V Leiden both cause still births and defects when you have the gene's.But I wonder can you have both gene's? I think I might get tested for MTHFR! and find out if I have it, and do more research to find out how the two gene's are similar.You can have both genes. I was recently diagnosed with both mutations (heterozygous in both cases). Currently my Doc has me on aspirin and Prenate. They are similar in that they both carry an increased risk of blood clots.
    Anonymous 42789 Replies Flag this Response
Thanks! A moderator will review your post and it will be live within the next 24 hours.