Discussions By Condition: I cannot get a diagnosis.

Low WBC - Drs have no clue

Posted In: I cannot get a diagnosis. 6 Replies
  • Posted By: gemgal
  • January 19, 2009
  • 08:41 PM

I have a consistently low white blood cell count first found two years ago when I had mono. It crept back up to normal but then again fell back down this summer. It's been between 2.5 and 3.9 since august. I had the following tests:

-I had a bone marrow aspiration - No leukemia / No Lymphoma
-I had a blood smear - White blood cells appear large
-Tested negative for lupus, HIV (twice tested) and Rheumatoid arthritis
-I was told I do not have a vitamin B (12?) deficiency.

I went to two hematologists and their answer was to monitor me since I am showing no other symptoms. I had the flu a few weeks ago, but everyone else around me caught it too. I also had a root canal that still got infected and had to repeat the root canal on the same tooth. Other than that, I'm pretty ok.

As for family history, my mother also had a similar issue and her bone marrow tested. I would want to say its genetic, but I don't have a clue where to research this.

What else could this be? What other tests can I ask for? I just want to put a name to this. A clue in any direction would help.

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6 Replies:

  • Yes, it is possible for your WBCs (leukocytes) to be influenced by genetics, and yes, there are genetic conditions in which people have low WBC. If you're in doubt, ask to see a geneticist.
    aquila 1,263 Replies
    • January 20, 2009
    • 06:09 PM
    • 0
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  • What you have is called neutropenia.It can be caused by several things.Are you on any type of medication?
    richard wayne2b 1,232 Replies
    • January 20, 2009
    • 09:01 PM
    • 0
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  • Actually,I misread your post.It's called leukopenia since I don't have the WBC differential count.Can you give it to me ?
    richard wayne2b 1,232 Replies
    • January 20, 2009
    • 09:05 PM
    • 0
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  • You mentioned you mother, does she have a low white blood cell count? If it is genetic or possibly genetic, then this should help in determining whether it is genetic. There's over a doxzen different causes of a low white blood cell count including medicines you may be taking, vitamin deficiencies or even a parasitic disease.
    Anonymous 42,789 Replies Flag this Response
  • You mentioned that you have had a root canal, which would lead me to believe that you have at least some of your own teeth. Do you, by any chance, also have any dentures or partials? I ask because my mother suffered from this same problem (and others), and also tested negative for lupus, RA, etc. After she passed away we finally figured out that she was suffering from hyperzincemia and hypocupremia, caused by the zinc in her denture cream. If you do wear dentures, and use denture adhesives, I strongly suggest looking into zinc free denture adhesives.
    Anonymous 42,789 Replies Flag this Response
  • I have low count of WBC (2.1 to 2.5) all my life. I have done all the tests including bone marrow test. The test results show that everything is normal with me. Doctors couldn't find anything wrong. I feel pretty healthy. Recently I found all my siblings have low white blood cell count. Now I believe it is genetic.
    Anonymous 1 Replies
    • November 29, 2015
    • 04:11 PM
    • 0
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