Discussions By Condition: I cannot get a diagnosis.

Long complicated story

Posted In: I cannot get a diagnosis. 7 Replies
  • Posted By: WitchKagome
  • August 8, 2008
  • 03:38 AM

Ok this all started a year ago. I woke up one morning after a full nights sleep and felt like I haddn't slept at all I went to work kept falling asleep while driving got to work was barely awake standing up they sent me on break slept on break sent me home early slept in my car woke up kept trying to fall asleep on the road just across town got home fed me and my two kids went to sleep woke up when it was time for kids to go to bed and then slept all night.
Ok this went on for three days and on the third day I was confused and dissorianted (sp) went to the er got sent home said need to get sleep
Ok I did this routine of mine for four to five days stait then I would have a day where I was awake for half or sometimes I got lucky and it would last all day.
On my day off I slept all day
I lost weight 27 pounds (I am overweight) without eating any different. My doc put me through a ton of tests
Finally he ran a test on my cortisal levels just a morning am drawing of blood not the good adisson's test. They were low
I got put on the flornef and hydrocortisone. And I was awake again!
I thought I was all fixed
but no I started getting tremors in my hands head and sometimes my legs. I also have a hard time walking when this happens and often fall. this happend about for a week out of every two months.
Now it is about twice a week I go through this.
I got an MRI of my brain and it was normal i went to a neorolagist the same one my son sees for his seizures and he looked at my file and said oh you have a history of anxiety so I went from clonazapam to valium. Back on lexapro and Welbutrin.
It didn't help just got worse over time. I even have them in my sleep and I found out my Brother has mystery undiagnosised tremors. He lives in Florida I am in Kansas. He went to the er only once and they said it was from him smokeing pot. He hasn't seen a doc sence he just deals with them.
I don't smoke pot, I hardly ever drink the only drugs I take are the ones the doc writes me.
I have no clue what is going on. I have been to the ER several times and my docter.
I see an endocronolagist (big sp) next month.
Anyone have a clue what is going on?
I am 31 overweight but lossing it (on purposs this time) I have two bulging disks in my spine
my doc has me on: Lexapro, welbutrin, valium, tylonal 3, Hydrocortisone, flornef, I think that is it.

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7 Replies:

  • Interactions between your selected drugshttp://www.drugs.com/images/s3.jpg Wellbutrin (buPROPion) and hydrocortisone (Major Drug-Drug)MONITOR CLOSELY: The use of bupropion is associated with a dose-related risk of seizures. The estimated incidence of seizures is approximately 0.1% at dosages up to 300 mg/day and 0.4% at dosages between 300 to 450 mg/day, but increases almost tenfold between 450 mg and 600 mg/day. The risk may also be increased during coadministration with selective serotonin reuptake inhibitors (SSRI antidepressants or anorectics), monoamine oxidase inhibitors, neuroleptic agents, central nervous system stimulants, opioids, tricyclic antidepressants, other tricyclic compounds (e.g., cyclobenzaprine, phenothiazines), systemic steroids, and/or any substance that can reduce the seizure threshold (e.g., carbapenems, cholinergic agents, fluoroquinolones, interferons, chloroquine, mefloquine, lindane, theophylline). These agents are often individually epileptogenic and may have additive effects when combined.MANAGEMENT: Extreme caution is advised if bupropion is administered with any substance that can reduce the seizure threshold, particularly in the elderly and in patients with a history of seizures or other risk factors for seizures (e.g., head trauma; brain tumor; severe hepatic cirrhosis; metabolic disorders; CNS infections; excessive use of alcohol or sedatives; addiction to opiates, cocaine, or stimulants; diabetes treated with oral hypoglycemic agents or insulin). Bupropion as well as concomitant medications should be initiated at the lower end of the dose range and titrated gradually if feasible. The total dose of bupropion should generally not exceed 450 mg/day (or 150 mg every other day in patients with severe hepatic cirrhosis). Bupropion should be discontinued and not restarted in patients who experience a seizure during treatment.http://www.drugs.com/images/s3.jpg Wellbutrin (buPROPion) and Florinef Acetate (fludrocortisone) (Major Drug-Drug)MONITOR CLOSELY: The use of bupropion is associated with a dose-related risk of seizures. The estimated incidence of seizures is approximately 0.1% at dosages up to 300 mg/day and 0.4% at dosages between 300 to 450 mg/day, but increases almost tenfold between 450 mg and 600 mg/day. The risk may also be increased during coadministration with selective serotonin reuptake inhibitors (SSRI antidepressants or anorectics), monoamine oxidase inhibitors, neuroleptic agents, central nervous system stimulants, opioids, tricyclic antidepressants, other tricyclic compounds (e.g., cyclobenzaprine, phenothiazines), systemic steroids, and/or any substance that can reduce the seizure threshold (e.g., carbapenems, cholinergic agents, fluoroquinolones, interferons, chloroquine, mefloquine, lindane, theophylline). These agents are often individually epileptogenic and may have additive effects when combined.MANAGEMENT: Extreme caution is advised if bupropion is administered with any substance that can reduce the seizure threshold, particularly in the elderly and in patients with a history of seizures or other risk factors for seizures (e.g., head trauma; brain tumor; severe hepatic cirrhosis; metabolic disorders; CNS infections; excessive use of alcohol or sedatives; addiction to opiates, cocaine, or stimulants; diabetes treated with oral hypoglycemic agents or insulin). Bupropion as well as concomitant medications should be initiated at the lower end of the dose range and titrated gradually if feasible. The total dose of bupropion should generally not exceed 450 mg/day (or 150 mg every other day in patients with severe hepatic cirrhosis). Bupropion should be discontinued and not restarted in patients who experience a seizure during treatment.http://www.drugs.com/images/s3.jpg Wellbutrin (buPROPion) and Lexapro (escitalopram) (Major Drug-Drug)MONITOR CLOSELY: The use of bupropion is associated with a dose-related risk of seizures. The estimated incidence of seizures is approximately 0.1% at dosages up to 300 mg/day and 0.4% at dosages between 300 to 450 mg/day, but increases almost tenfold between 450 mg and 600 mg/day. The risk may also be increased during coadministration with selective serotonin reuptake inhibitors (SSRI antidepressants or anorectics), monoamine oxidase inhibitors, neuroleptic agents, central nervous system stimulants, opioids, tricyclic antidepressants, other tricyclic compounds (e.g., cyclobenzaprine, phenothiazines), systemic steroids, and/or any substance that can reduce the seizure threshold (e.g., carbapenems, cholinergic agents, fluoroquinolones, interferons, chloroquine, mefloquine, lindane, theophylline). These agents are often individually epileptogenic and may have additive effects when combined.MANAGEMENT: Extreme caution is advised if bupropion is administered with any substance that can reduce the seizure threshold, particularly in the elderly and in patients with a history of seizures or other risk factors for seizures (e.g., head trauma; brain tumor; severe hepatic cirrhosis; metabolic disorders; CNS infections; excessive use of alcohol or sedatives; addiction to opiates, cocaine, or stimulants; diabetes treated with oral hypoglycemic agents or insulin). Bupropion as well as concomitant medications should be initiated at the lower end of the dose range and titrated gradually if feasible. The total dose of bupropion should generally not exceed 450 mg/day (or 150 mg every other day in patients with severe hepatic cirrhosis). Bupropion should be discontinued and not restarted in patients who experience a seizure during treatment.
    acuann 3080 Replies Flag this Response
  • You are on a scary cocktail of medications!:eek: I suggest talking with your docs about tapering off some of these meds. I also would consider B12 deficiency contributing to your tremors. But mostly I think you are having side effects form your meds causing your problems. Yikes! Please look into Traditional Chinese Medicine to help with your mental/emotional problems - it is VERY effective. Were you on clonazipam before the first episode of somnolence? What other medications were you on at that time? Clonazipam can cause somnolence (desire to sleep), and if you were taking a high enough dose it could have contributed to your original symptoms. Please research all your drugs on www.drugs.com or www.rxlist.com. Doctors won't do this - you need to be an educated consumer when it comes to the meds you are prescribed. Best wishesDOM
    acuann 3080 Replies Flag this Response
  • I didn't know that about the welbutrin I just started taking it yesterday. The clonazapam I only took when I had a panick so like maybe twice a month. I also rarely take the tylonal 3 only when my back pain gets so bad it hurts to walk. I go months at a time withought it. Now I only take the valium when I have a panick attack or to try and stop the tremors. It doesn't work LOL Most docs try to say the tremors are anxiety. I have never felt anxiety when it happens (except the first time) and i have had a couple of panic attacks since and never had the tremors. Also I can't talk sometimes during the tremors and when I can I studder. I went to the ER several times but once they gave an antiseizure drug adivant same thing the gave my son at the er now he takes depakote.The adivant (sp) injection stopped the tremors (thats the only thing that has ever worked) I told my doc all this and he still thinks if he gets my anxiety under control I will be fixed. I have had depression for years and tried lots of meds and the only thing that worked was welbutrin and lexapro together. I couldn't afford those meds I took them for like 4 years and when I left my husband I weened myself off cuz i couldn't afford them and I was shocked that My depression didn't comeback. (I have been depressed since I was about 8) I still havn't been depressed but he looked at my chart and decided to put me back on all of that. I started that yesterday I was on ultram for a while and my doc thought that may have been why the tremors got worse around the same time I started taking them. I have been completely off those for only a week after weening down.
    WitchKagome 1 Replies Flag this Response
  • Please do consider trying acupuncture and Chinese medicine to help get you back in balance. It can really make a difference and is a holistic form of medicine. Also, try to get copies of your blood work and check your serum B12 levels. If under 500 I suggest you may have B12 deficiency - this is very serious and can cause irreversible neurological damage if untreated. Most docs overlook this. If you know your levels and they are under 500, I suggest getting on the B12 Misdiagnosis thread and doing some research there ( it is a very long thread over 400 pages, but ver informative). Tremors are not caused by anxiety, but if you have neurological issues you may suffer from both symptoms. Please make sure you know your B12 levels. It also helps with depression! Best wishesDOM
    acuann 3080 Replies Flag this Response
  • Finally he ran a test on my cortisal levels just a morning am drawing of blood not the good adisson's test. They were lowI got put on the flornef and hydrocortisone. And I was awake again!I thought I was all fixed . What you said here concerns me. Those drugs are very serious drugs if taken if they werent truely needed as they can cause complete adrenal failure and then hence lifelong dependancy. My own cortisol levels are out of the normal range... abnormally low. But due to what those drugs can do, the endocrinologist (and two other doctors, one another specialist).. will not put me onto cortisol for my low cortisol, due to the likehood of making my condition worst in the long run. (thou studies in those with my condition, CFS have shown that we often do feel better and less tired on it.. a third of ones with CFS (chronic fatigue syndrome do have abnormally low cortisol). im truely concerned for you in the long run esp if your levels werent extremely low?? were they??? , (mine is 47 n/mol.. *normal is meant to be 50-350 n/mol) and seeing you didnt have the proper addisions test done after the cortisol test result. .................
    taniaaust1 2267 Replies Flag this Response
  • I suggest that you try the alternative treatments for anxiety, in section 6 of my website, at http://www.ezy-build.net.nz/~shaneris View page N first. It would not be advisable to discontinue Lexapro, (see www.theroadback.org on Lexapro) Wellbutrin, and Valium at the same time. I would leave the Valium to last, because it is a benzodiazapene, and will take a long time to wean off, safely. After 2 weeks of tapering off the first two, I would begin taking St. John's wort, or another herbal remedy for anxiety, with medical advice, and seek a second opinion: your doctor is prescription happy! A previous post follows: The subject of tapering off is addressed in section 2 of my website, at http://www.ezy-build.net.nz/~shaneris in the first 3 pages. Also see: WITHDRAWING FROM PSYCHIATRIC MEDICATIONS &MEDICATIONS: DIFFICULTY STOPPING PSYCHIATRIC DRUGS, in section 1. For the more difficult medications, the following is an option worth considering. For the 1st week, take a 90% dose, and in the 2nd, 80%, 3rd, 70%, and so on, down to 10%. Then, the next week, 9%, and the next, 8%, and so on, down to 1%. Then 0.9%, 0.8%, and so on every week, until at 0.1%, which is a thousanth the strength of the original dose. At this stage, depending on how you are reacting, ("brain shivers", "skin crawling sensations", etc.) you may elect to continue following the above procedure for one, two, or even three or four further stages, stretching the process out to more than a year. I know that this is not unreasonable, and mental health care providers sometimes recommend an even slightly longer time frame. Benzodiazapenes are included in the class of medications for which the above method may be indicated. Check out your medication(s) at http://www.drugs.com & http://www.rxlist.com to see which category yours fall into. Liquid versions of some medications are available, which makes this process much easier, so consult your prescriber, and get a plastic, graduated medicine measuring cup from a pharmacy. Otherwise, use a mortar and pestle. Put the powdered matter on a clean surface, and with a straight edge, make a long, thin line of it. When the quantities get small, it may help to add some water, to make your measurements more precise. You can then divide it into 2 equal halves, each 50%, then repeat the process, making a long, thin line, and dividing in half (=25%), and once more equals twelve and a half percent. Make a long, thin line of this, and divide into 5 equal parts. Four of those parts equals 10%. A small amount (1% - 3%) will unavoidably be lost in the above process. The rest I am unable to help you with, but you could try Yahoo!Answers: Health > Mental Health and Science > Medicine. Post seperate questions for both. Also try the forums in www.careplace.com & www.drugs.com
    shaneris 46 Replies
    • August 11, 2008
    • 05:57 AM
    • 0
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  • Besides meds side effects, do you have a carbon monoxide detector in your home? Check it out and make sure it is safe and then take it in.to your office and check there
    Monsterlove 2921 Replies
    • August 11, 2008
    • 06:49 PM
    • 0
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