Discussions By Condition: I cannot get a diagnosis.

Long Axonal Polyneuropathy

Posted In: I cannot get a diagnosis. 4 Replies
  • Posted By: Felsen
  • December 16, 2008
  • 10:54 PM

What is Long Axonal Polyneuropathy? Is there any working treatment? How is the prognosis? It's about a very sick friend of mine, 50 years old male, who also has the fibromyalgia diagnosis.

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  • Nothing at all in Medline for this exact term. Try this: 1: J Clin Neuromuscul Dis. 2007 Sep;9(1):265-76.Approach to vasculitic neuropathies.Lacomis D, Zivković SA.Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh,Pennsylvania, USA. lacomisd@upmc.eduSince vasculitic neuropathy is treatable and potentially debilitating, cliniciansshould develop an approach to neuropathy that increases the likelihood ofuncovering existing systemic or nonsystemic vasculitis. The presence of aconnective tissue disease, systemic vasculitis, asymmetric ornon--length-dependent axonal polyneuropathy, or multiple axonal mononeuropathies should heighten suspicion, but vasculitic neuropathy can also present as a distalsymmetric polyneuropathy with or without other organ involvement.Electrodiagnostic testing utilizing extensive nerve conductions may be helpful inidentifying features suggestive of vasculitic neuropathy and in selecting anabnormal nerve and muscle for biopsy confirmation. An array of laboratory testsmay lead to identification of a systemic disorder that is either characterized byor predisposes to vasculitic neuropathy. The mainstays of treatment arecorticosteroids and cyclophosphamide, but other drugs are used in specificconditions. With early diagnosis and careful monitoring of treatment regimens,the prognosis is usually good.PMID: 17989592
    aquila 1263 Replies
    • December 19, 2008
    • 08:55 PM
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  • Thank you, Aquila for all the info.
    Felsen 510 Replies
    • December 24, 2008
    • 08:36 PM
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  • Anyone else? Dr Cottle?
    Felsen 510 Replies
    • December 30, 2008
    • 00:38 AM
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  • Dear Aquila,My father also has axonal polyneuropathy and we see that lately it is getting worse. I live in Geneva, Switzerland and my father lives in Baku, Azerbaijan. Unfortunatelly we can't find any treatment for him. Is there somewhere in the world is existing a medical center specialesed on this?Many thanks in advance.
    yadigar 1 Replies
    • November 10, 2013
    • 06:19 PM
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