Discussions By Condition: I cannot get a diagnosis.

High Pancreatic levels but nothing wrong

Posted In: I cannot get a diagnosis. 2 Replies
  • Posted By: twhite805
  • September 9, 2010
  • 06:59 PM

I have been sick for over 9 years and nobody can tell me what is wrong. I have severe stomach pain at times that sends me to the hospital at least once a year. The last two times I went to the hospital my pancreatic levels were sky high but they say my pancreas is fine and they can't tell me why my levels are so high. I have back pain all the time, part of it is caused by two tared disks but it seems like my stomach pain causes my back to hurt. I also have acid reflux and take nexium every day if I miss a day I feel like I am dying. I also have a lot of other weird symptoms including muscle spasms, headaches, throat pain (not from the acid) and blurred vision. It seems like I have had every test under the sun including X-rays, MRIs, cat scans. upper and lower GIs even a spinal tap. Any advice would be greatly appreciated.

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  • Interesting how they say your pancreas is "fine" when the enzymes are sky high. I assume they did an MRI an found no tumor. Still upper abdominal pain and high enzymes sounds like pancreas to me, and an angry pancreas is nothing to ignore. It might be a shot in the dark, but one thing you could try that couldn't hurt is a supplement called PPC (polyenylphosphatidylcholine), brand names PhosChol, HepatoPro (and Essentiale Forte in Europe). PPC is simply a highly refined and concentrated form of polyunsaturated Lecithin, which contains a much higher ratio of DLPC (Dilinoleoylphosphatidylcholine) which has shown in animal studies to greatly reduce inflammation and oxidative stress in the liver and pancreas. I was having some liver issues, and PPC fixed me right up. Now I tell everyone I can about how well it helped me. I'm not a doctor... Just someone who was helped by PPC and now I spread the word. Alcohol is often what irritates the pancreas, but even if you don't drink, it appears something is irritating yours. I think high triglycerides can irritate it too. Here's a couple of quotes on how well PPC fixes pancreatic inflammation in studies with alcohol. Overlooked & OverworkedPreventive maintenance for your stomach, liver and pancreasKarin Granstrom Jordan, MD"DLPC appears to be primarily responsible for many of the protective actions of PPC on the liver and pancreas".The pancreas is essential to both digestion and glucose regulation. It secretes digestive enzymes into the duodenum for protein, carbohydrate and fat digestion, and produces large amounts of sodium bicarbonate (as found in baking soda) to neutralize stomach acid in the duodenum. The islets of the pancreas produce insulin and the related hormones glucagon and somatostatin.Pancreatitis-inflammation of the pancreas-is caused primarily by overconsumption of alcohol in about 80% of cases. Ethanol causes severe oxidative stress in the pancreas, probably due to increased production of free radicals and depletion of glutathione and other antioxidants. In particular, both alcohol intake and pancreatitis are associated with rises in the CYP 2E1 enzyme in the pancreas.The research group that investigated the correction of alcohol-induced liver damage by PPC has recently published research demonstrating the same protective effect in the pancreas (Aleynik SI, Leo MA, Aleynik MK et al., 1999). When rats were given ethanol, markers of oxidative stress in the pancreas rose sharply. However PPC given along with the ethanol prevented this rise, and almost completely alleviated the depletion of pancreatic glutathione caused by ethanol.The protective effect of PPC on oxidative stress in the pancreas was even more pronounced than these researchers had observed in the liver of baboons fed alcohol. PPC may protect the pancreas from other causes of oxidative stress; as the authors state, PPC "could provide innocuous but effective and orally active antioxidant therapy, not only as shown before for liver injury, but also, as shown here, for early pancreatic changes."PPC is also good for your stomach:"Doses of aspirin as low as 30 mg suppress the production of protective prostaglandins in the gastric mucosa. In addition, aspirin's direct contact with the gastrointestinal tract interferes with the hydrophobic "non-wettable" properties that protect the underlying epithelium from gastric acid and other toxic substances. This characteristic seems to be attributable to an extracellular lining of phospholipids, which are synthesized in surface mucus cells of the stomach. Aspirin and other NSAIDs can rapidly transform the gastric mucosa from a non-wettable to a wettable state, thereby increasing the tissue's susceptibility to the corrosive actions of gastric acid"."A study on experimentally induced gastric ulcers in rats (Dunjic BS, et al., 1993) showed that mucosal lesions were significantly reduced by a single dose of PPC given before or after the injury factor, which in this study was ethanol or an NSAID.A recent clinical trial compared the GI effects of aspirin to those of aspirin complexed with PPC (Anand BS et al., 1999). Sixteen healthy subjects were given either ten doses of aspirin or ten doses of the aspirin/PPC complex over a 72 hour period. After a "washout" period, subjects were switched over to the other medication for a 72 hour period.Researchers counted the number of gastroduodenal erosions in each subject. Those taking aspirin had an average of 8.75 erosions, while those taking the aspirin/PPC complex averaged only 2.81 erosions. The protective effect of PPC was most apparent in those who were most susceptible to aspirin injury, and did not interfere with the therapeutic activity of the aspirin".I think if you gave PPC a try you might be surprised... I may take a month before you feel better, but you should notice improvement fairly soon. Good Luck & GodSpeed
    synesthesia 87 Replies
    • September 10, 2010
    • 05:40 AM
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  • I think you may have insulin resistance. Get a doctor to send you for a 2 hour glucose tolerance test (that also checks the insulin in response to glucose). I have insulin resistance and it causes me to have to take nexium due to the reflux. (that would fit probably the pancreas stuff too as they produce insulin and in insulin resistance.. too much insulin is being produced.. so maybe your pancreas are overworking!! due to this) Insulin issues can cause your other symptoms too.
    taniaaust1 2,267 Replies
    • September 11, 2010
    • 05:46 PM
    • 0
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