Discussions By Condition: I cannot get a diagnosis.

Help - fatigue, peripheral neuropathy, chroinic sinus

Posted In: I cannot get a diagnosis. 1 Replies
  • Posted By: Anonymous
  • November 1, 2009
  • 00:04 AM

I have fatigue, chronic long lasting sinus infections (3-4 months even with lots of antibiotics), and peripheral neuropathy. My spinal fluid shows slightly elevated protein. I have a great neurologist and he's out of ideas so I'm thinking chronic infection or autoimmune. Normal bloodwork and immunoglobulin A, G, and M tests show nothing. Any ideas?

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  • I am sorry that you have these problems I would undergo the following Review of hormone levels in particular am cortisol, LH, FSH, SIBGH TSH, PTH, VitD, testosterone (low testosterone can be related to chronic fatigue), insulin levels, blood sugars, other autoimmune markers and markers for bone inflammation. Also I would review your iron stores in particular ferritin levels - low iron is also related to fatigue Other blood tests: tumor markers for liver, gut (CEA) and chomogranin A Some imaging - CT of the sinus cavity, chest x-ray if these are negative and you still feel unwell I would recommend a PET scan as you have some peripheral neuropathy - this may show any cancer including blood cancers like lymphoma that can affect the body causing infections, abnormal neuropathy. Let me know how you are going Cheers I have fatigue, chronic long lasting sinus infections (3-4 months even with lots of antibiotics), and peripheral neuropathy. My spinal fluid shows slightly elevated protein. I have a great neurologist and he's out of ideas so I'm thinking chronic infection or autoimmune. Normal bloodwork and immunoglobulin A, G, and M tests show nothing. Any ideas?
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