Discussions By Condition: I cannot get a diagnosis.

Help aso titer elevated with no symptoms

Posted In: I cannot get a diagnosis. 2 Replies
  • Posted By: kdudley
  • March 29, 2012
  • 02:44 AM

I need help my son that is 6 years old was diagnosed with ADHD by his pediatrician and put on Vyvanse 20 mg. He took this stregnth for 2 weeks and it seemed to work miracles, Unfortunately on the 3rd week it was not effective at all it appeared as if he was not even taking the medication at all. His pediatrician uped his dose to 30mg at the end of the 3rd week. It was 11 days after that when I noticed that he could not function properly. He looked as if he was having seizures to me but later found out it wasn't. His hands were flexing uncontrolably open and close to the point he would try to sit on them to get them to stop, his eyes would **** to the side and look like they were trying to roll in the back of his head and stay a second or so before returning to normal, he developed this wiping thing where he uses the outside palm area to wipe at his eyes, nose, and mouth to the point that it is very red almost raw; and he also pokes at his ears as if trying to pop them. After trips to the er and his pediatrician we found out his ASO Titer was elevated to 1151. He was put on antibiotics for 10 days and then sent to a nuerologist when the symptoms continued, the hand flexing and eye jerking stopped but then his hands started this rubbing motion of the first finger ontop of the second finger. He was also very emotional and seemed as if he reverted back to when he was 3 years old and yes we did stop the vyvanse. After the nuerologist appointment she decided to continue for 10 more days on antibiotics and then retest the ASO Titer. The second test revealed a result of 632 which was better but the hands and rubbing and emotional issues remained the same. Then we were sent to an Infectionous Desease Specialist 13 days later that retested the ASO Titer and at this time revealed a 1060 result. So, I am now lost, confused, and extremely worried about my 6 year old son that continues to ask when can go to a doctor that will fix me mommy. It breaks my heart to not be able to fix his problems any and all suggestions would be greatly appreciated. Just to inform you everything but the symptoms and ASO Titer is completely normal. He has never had strep or throat infection since he was born. Please help.

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  • ASO titers measure the antibodies produced after a streptococcal infection.It is possible, I suppose, that your son could have had an infection without you knowing.The thing is that I was just reading about how these ASOs are produced slowly in response to the chemicals that the streptococci produce so that they ( the strep bacteria) can remain hidden from the human hosts immune system. Thus they are very like huuman proteins and the human body can get mixed up and start to produce anitbodies against its own proteins and attack them.Now the article was about how these antibodies can attack protein in and around the brain leading to obsessive compulsive disorder (OCD) and your son does seem to be displaying signs of OCD.So I think your doctors may be on the right track in trying to bring down his ASO levels.After I post this I will try and find that article for you.
    chrismia 159 Replies Flag this Response
  • I wrote a long explanation but this site no longer seems to recgnise me.http://serendip.brynmawr.edu/exchange/node/1769ASO titers have been linked to OCD. The above link will help but google OCD and ASO titers.Your doctors are right to get those ASO levels down
    chrismia 159 Replies Flag this Response
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