Discussions By Condition: I cannot get a diagnosis.

FBC abnormalities (need professional help)

Posted In: I cannot get a diagnosis. 0 Replies
  • Posted By: Anonymous
  • January 12, 2009
  • 07:34 AM

Hi

I need a second opinion on the results below
What is the classification & diagnosis of this disorder?

Please advise. Thank you.

Male
40 year-old

FBC Results
RBC 2.3 x 10^12/L
WBC 5.6 x 10^9/L
Haemoglobin 5.4 g/dl
Haematocrit 17.0%
MCV 73.9fl
MCHC 31.8%
Platelets 19 x 10^9/L
Neutrophils 4.95 x 10^9/L (85.1%)
Lymphocytes 0.8 x 10^9/L (13.4%)
Monocytes 0.04 x 10^9/L (0.5%)
Eosinophils 0.002 x 10^9/L (0.04%)
Basophils 0.05 x 10^9/L (0.76%)
Blast 3%
Promyelocytes 85%
Myelocytes 10%
Metamyelocytes 2%
Malarial parasite Negative
Other comments Nil

Coagulation Test Results
PT 20 sec
APTT 52 sec
TT 30 sec
Fibrinogen 0.1g/l
FDP 35ug/ml

Bone marrow
Blast 9%
Promyelocytes 70%
Other findings Hypercellular
Numerous Auer rods (faggots)

Hb Electrophoresis
Hb A2 2.5%
Hb F 0.8%

MY CONCLUSION
Microcytic hypochromic with immature blasts, thus possible AML. Is it M3 using the FAB classification?
But does he have thalassaemia?
What kind of cytochemical stains should I perform if i could?

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