Thanks in advance for your insight and guidance. In March I suddenly found myself with a range of new diagnoses after being completely healthy 45 year old male with no medical history. In March 2009 I was diagnosed with Eosinophilia (40%), Hypogammaglobulinemia low IgG (407) after going to the doctor with stomach pain and alcohol intolerance (0.5 ounce of wine or whiskey would trigger a violent attack within minutes, while grape juice does not cause an attack). Asthma (85% lung capacity), lung granulomas, lung nodules and possible mild Bronchiectasis.
This all occurred after starting a 30 day course of Canasa (Mesalamine) to which I had rash and breathing problems in what seems to have been an allergic reaction and possibly triggered the above problems.
I am now on Claritin (10mg), Lexapro (5mg) and Aciphex which together brought relief to stomach pain within hours.
Cardiologist sees no Eosinophilic infiltration or Loeffler’s.
Repeated Endoscopies show no problems. I am negative for Eosinophilic Gastroenteritis.
3 day stool test for parasites came up negative.
Hematologist did bloodwork and Bone Marrow biopsy, but sees no sign of neoplastic disease.
Combining this with the gastric disturbance/attacks (with instant continual relief with Claritin), alcohol intolerance, lung granulomas, lung nodules, sudden onset Asthma, all right after a reaction to Canasa, is an quite a set of symptoms that I think merits a 2nd opinion before going down steroids to control Eosinophilia and/or regular IV Immonoglobulin for the low IgG (note I do not get infections).
My internist feels very uncomfortable with two concurrent diagnoses of very rare disorders (Eosinophilia and Hypogammaglobulinemia). Thoughts? Suggestions?
Warm regards, thanks in advance,