Discussions By Condition: I cannot get a diagnosis.

Conflicting lab results, need pointer

Posted In: I cannot get a diagnosis. 3 Replies
  • Posted By: aakopyana
  • April 16, 2008
  • 06:57 AM

Hi.

8 Y male obese child presents with mild abd discomfort, loose stools, fatigue.

Routine blood tests reveal the following

RBC 5.37 H
Segs 17.0 L
Lymphs 64.7 H
Eosinophils 9.7 H

BUN/CR Ratio 28 H

Incidentally Chollesterol is 225 (HDL 72 LDL 136)

So far i am thinking parasites, can someone help point me in the right direction?

Thanks

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3 Replies:

  • Sounds that way to me, abdominal infection of some sort. Has a stool examination (parasites) been suggested? To note that these tests have a high rate of false negatives, it is normally recommended that several samples are submitted. You might want to reference Dr. Leo Galland's work on parasitology.
    LINENUP 122 Replies Flag this Response
  • Increased red count and BUN/Cr ratio could be dehydration secondary to the diarrhea. Diarrhea could be from parasite infection. Not sure how to explain elevated lymphs. Both eos and lymphs can be up in leukemia, but I don't know if they would both be up together since they are from different lineages.To play it safe, you may want to refer to GI or do more research to see what might explain the lymphocytes (in exchange for polys). Perhaps there is another chronic infection secondary to the parasites?Sorry this isn't much help.Best Wishes.
    Anonymous 42789 Replies Flag this Response
  • I think there's also a rare bowel disease with eosinophic infiltration in which patients are intolerant of different kinds of food and have widespread diarrhea after eating. I'm not sure what it's called, or whether it produces eosinophilia in the serum... but it's not parasitic- it's more of an allergic reaction.I'm wondering if it might help if you did a pub med search for "lymphocytosis in parasite infections" to see if you can get increased lymphocytes in parasite infections. I looked up lyphocytosis in one of my lab manuals and did not see parasite infection listed on the differential, but the books I use may not be all that accurate.Good Luck!
    Anonymous 42789 Replies Flag this Response
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