I have been getting the hives now for about 3 months, and my lip has also been swelling. Went to an allergist and he did an allergy test and a blood serum test, his conclusion was that my body is producing an antibody that is causing the hives and angioedema...so basically I am allergic to myself and there is nothing he can do about it. I take 2 zyrtec a day and a nexium, but it does not help, I have gone through rounds of taking predisone and it clears it up, but as soon as it is out of my system, the hives and swelling are back. I need help because this is absolutley driving me insane, should I get a second opinion, should I see a dermatologist instead of an allergist? I stay upset about it...praying, crying, and I know the crying doesn't help it but I can't help it. How can a person be allergic to their own body? Any suggestions would be helpful. I have stopped drinking cokes, cheese, lunchmeats because I read where these foods make your body make histamine, I will try anything to get rid of this.