My husband has been experiencing recurring bacterial infections which form abcesses requiring surgery in his right calf and foot. He has been hospitalized 5 times now since July 08 (most recently last week). On one occasion he became septic and developed abcesses in his left hand and foot. He does not have diabetes and is not HIV positive.
The bacteria which is growing are citrobacter freundii, klebsiella pneumoniae and escherichia coli. The doctors have done several CT's of his abdomen and see no visible bowel leaks and he has no problem "passing food". He has not had any abcesses on his abdomen or buttock so they have ruled out any leaks from the bowels.
He was taking Raptiva (immunosuppressant) for several years and then was changed over to Enbrel (immunosuppressant) for 6 months before the first sign of infection. At that point all immunosuppressants have been stopped.
He has been on several antibiotics (oral and IV) which do seem to clear up the infections (after surgery) however, within 10-14 days of stopping the antibiotics the infections reappear.
The doctors are at a loss. Most feel it is immunological and that his body just can't fight the microbes of bacteria entering his skin through even hair folicles. Others feel it could be microscopic bowel leaks somehow making it's way to the extremities.
I would just like a diagnosis so we know how to prevent these in the future.
Any ideas would be greatly appreciated!