Discussions By Condition: I cannot get a diagnosis.

Cancer, Multiple Sclerosis, Bipolar II disorder?

Posted In: I cannot get a diagnosis. 8 Replies
  • Posted By: SCORPIAN5
  • July 2, 2007
  • 04:42 PM

Hi,

My sister has recently, well for the past year, has had the following symptoms. The doctors performed a blood test to test for liver functions, glucose {diabetes}, and TSH thyroid hormone levels to check for any thyroid disorder. The blood test came back clear for all of these, and her GP has simple put it down to stress. The thing is though, she claims she is not stressed; she regularly, well too often, relaxes, goes on holidays, out with friends, ect. I do not personally believe it is due to stress.

I will appreciate any advice or suggestion on finding the correct diagnosis.

Somatic Symptoms

o Tight feeling in neck
o Difficulty breathing & swallowing
o Dyspnoea - Heavy breathing - panting
o Severe stomach aches and pains - extremely painful on empty stomach {abdominal CT scan}
o Fatigue, loss of strength in arms
o Muscular spasms –twitches, at night, unable move body can’t talk eyes open
o Full body nervous twitches
o Nervous tremors/shivers down the spine/entire body tremors/hands and arms frequently
o Bulging eyes
o Swollen lymph in neck {cervical lymph node}, lump developed gradually, yet painless mostly.
o Painful swallowing/breathing, possibly due to lymph node being swollen
o Ear popping, like at high altitude, very painful
o Pale skin
o Low blood pressure
o Fatigue – constantly feeling exhausted
o Hypersomnia
o Confusion, indecisiveness
o Difficulty concentrating
o Nausea
o Palpitations
o Atrial fibrillation - abnormal heart rhythms was checked at hospital, doctors suggested a pacemaker
o pass stools more frequently than normal
o a fast and sometimes irregular pulse
o warm clammy hands
o an increased thirst
o increased metabolism – hunger increased, cravings for carbohydrate rich foods, especially morning – improves mood sad>happy
o Itchy skin – arms mostly
o Mouth ulcers
o Blurred vision - frequently
o back pain – lower back, shoulder blades most severe.
o Thinning of hair, and hair loss
o Temperature regulation irregular –Feel very cold, at room temperature.


Psychological Symptoms

o Euphoric mood, then sad, variable mood swings {not anger}
o Panic – induces tremors
o Anxiety – Depersonalisation {frequently}, Derealisation {infrequent} - feeling cut off or distant from the immediate surroundings. Possibly the onset of depression or an anxiety disorder
o Forgetfulness – short term memory loss
o restlessness
o nervousness
o irritability


From my research online i have found that these symptoms could be related to the following diseases:

Medical Conditions That Can Cause such symptoms:
• Thyroid Disorders – over active thyroid -RULED OUT BY BLOOD TEST
• Thyroid cancer - ?
• Multiple Sclerosis - ?
• Bipolar II Disorder - ?
• Anxiety Disorder - ?
AIDS - VERY UNLIKELY
• Epilepsy - ?
• Vitamin B12 deficiency - ?
• Adrenal Disorders - ?
• Head Trauma - VERY UNLIKELY
• Lupus - ?
Diabetes - RULED OUT BY BLOOD TEST


If anyone can relate or help on the diagnosis, i will appreciate any feedback.

I have suggested the doctor to perform the following further tests:

1)Lymph node biopsy
2)CT scan of abdomen/throat

Yet my ignorant GP is certain its just stress. Bu that does not explain the heavy breathing constantly, even when she is relaxed and talking to friends, or the clearly visible lump in her neck {swollen lymph node which is painless and has grown gradually, it onyl hurts during swallowing of food and sneezing}, the palpitations, spasms, nervous twitches, low blood pressure/pale skin, fatigue, and how she feels freezing cold on a hot summers day - she puts the heater on when its 30oC outside, and has 2 blankets!. I understand that many of the symptoms may be related to simply stress, but the thing it my sister has a Type B personality, a very relaxed individual, not competitive, and unlikely to get stressed. She is 21 years of age and is about to graduate, there really is little to be stressed about at this stage.

Reply Flag this Discussion

8 Replies:

  • Has her doctor considered chronic fatigue syndrome? Please read the thread titled "The truth about CFS/ME. You will find all of her symptoms listed in the post showing symptoms of CFS/ME.I wish her well...she's lucky to have you...mommy cat:)
    mommy cat 1654 Replies Flag this Response
  • OSA Obstructive Sleep Apnea Does she sleep with out any upper respiratory blockage?
    armyranger 3 Replies Flag this Response
  • My sister has recently, well for the past year, has had the following symptoms ... and TSH thyroid hormone levels to check for any thyroid disorder. The blood test came back clear Define clear. Were a TSH, Free T3, Free T4, and thyroid antibodies tests done? Where are the results? Post the test ranges and the test results. Clear doesn't mean anything to me. Numbers and symptoms mean something. I've heard the same thing for too for years and years ad nauseum and was erroneously diagnosed with Fibromyalgia in 2000 when in fact I had Hashimoto's Thyroidits! I suffered needlessly for most of my life because doctors told me my thyroid tests were "normal" or "clear." I never asked for the test results and I needed to. I do now.With Hashimoto's you can have near normal or below normal TSH levels. You can have both hypo and hyper symptoms at the same time, which can make a diagnosis difficult. With Hashimoto's you can have flu-like symptoms. An experienced Endocrinologist who is up to date on the latest treatment protocols for Hashimoto's would be able to diagnose and treat someone.I listed your symptoms below and put the ones common to Hashimoto's in bold. Also with thyroid disease you can have sleep apnea and some of these symptoms are the same as that condition. I will underline the ones which are common to sleep apnea.Somatic Symptoms o Tight feeling in necko Difficulty breathing & swallowingo Dyspnoea - Heavy breathing - pantingo Severe stomach aches and pains - extremely painful on empty stomach {abdominal CT scan}o Fatigue, loss of strength in armso Muscular spasms –twitches, at night, unable move body can’t talk eyes openo Full body nervous twitcheso Nervous tremors/shivers down the spine/entire body tremors/hands and arms frequentlyo Bulging eyeso Swollen lymph in neck {cervical lymph node}, lump developed gradually, yet painless mostly.o Painful swallowing/breathing, possibly due to lymph node being swolleno Ear popping, like at high altitude, very painfulo Pale skino Low blood pressureo Fatigue – constantly feeling exhaustedo Hypersomniao Confusion, indecisivenesso Difficulty concentratingo Nauseao Palpitationso Atrial fibrillation - abnormal heart rhythms was checked at hospital, doctors suggested a pacemakero pass stools more frequently than normalo a fast and sometimes irregular pulseo warm clammy handso an increased thirsto increased metabolism – hunger increased, cravings for carbohydrate rich foods, especially morning – improves mood sad>happyo Itchy skin – arms mostlyo Mouth ulcerso Blurred vision - frequentlyo back pain – lower back, shoulder blades most severe.o Thinning of hair, and hair losso Temperature regulation irregular –Feel very cold, at room temperature.Psychological Symptomso Euphoric mood, then sad, variable mood swings {not anger}o Panic – induces tremorso Anxiety – Depersonalisation {frequently}, Derealisation {infrequent} - feeling cut off or distant from the immediate surroundings. Possibly the onset of depression or an anxiety disordero Forgetfulness – short term memory losso restlessness o nervousnesso irritabilityIf her thyroid is inflammed, enlarged, she could have enlarged lymph nodes. She also could have a concurrent condition/disease.Suggested reading on the web would be:http://www.thyroidmanager.org/Very technical but gives details of the symptoms you can have with Hashimoto's. http://www.thyroidtoday.com/Read the article under Expert Opinions by Carole Spencer. Gives protocol for diagnosing and treating thyroid disease.http://www.endocrineweb.com/http://www.apneasupport.org/http://www.sleepnet.com/how she feels freezing cold on a hot summers day - she puts the heater on when its 30oC outside, and has 2 blankets!. That's what I was doing for the past 6 months because I was being under treated for hypothyroidism. I couldn't get warm and turned the heat up to 75 degrees F inside our home while I shivered and shook under a heated blanket!Of course there could be other causes for these symptoms too. I've given you my version and take on what your sister's symptoms could mean based on my experience.
    Anonymous 42789 Replies Flag this Response
  • Or Graves disease.
    rad-skw 1605 Replies Flag this Response
  • I would recommend seeing another doctor about a thyroid disorder, preferably an Endocrinologist. I was recently diagnosed with Hashimoto's thyroiditis and the majority of my TSH and T4 tests have been normal, except for a couple that led my endocrinologist to make the diagnosis of Hashimoto's. It is very important to see a doctor that also takes family history and symptoms into account. Thryoid levels fluctuate with Hashimotos and you can oscillate between hyperthyroidism and hypothyroidism. I also have multiple sclerosis, so I would recommend having an MRI done. I have no idea which of my symptoms are caused by which disease but I have a lot of similar symptoms to what you have listed. I hope you are able to find a diagnosis soon and receive treatment. Some doctors believe that if you start treatment early enough it may be possible to reverse the disorder, and if not treatment will probably help. I don't think I have found my magic number of thyroid replacement hormones, because I have not seen a lot of improvement in my symptoms, but I am hopeful. Of your list these are the symptoms I also have.o Tight feeling in necko Difficulty breathing & swallowingo Dyspnoea - Heavy breathing - pantingo Severe stomach aches and pains - extremely painful on empty stomach {abdominal CT scan}o Fatigue, loss of strength in armso Muscular spasms –mine happen throughout the day. Accompanied with anxietyo Full body nervous twitcheso Nervous tremors/shivers down the spine/entire body tremors/hands and arms frequentlyo Pale skin- though I have always had pale skino Low blood pressureo Fatigue – constantly feeling exhaustedo Hypersomniao Confusion, indecisivenesso Difficulty concentratingo Nauseao Palpitationso a fast and sometimes irregular pulseo an increased thirsto increased metabolism – hunger increased, cravings for carbohydrate rich foods, especially morning – improves mood sad>happyo Itchy skin- all overo Mouth ulcers- i have had these in the past, they come and disappear, starting as tiny bumps on my lipso Blurred vision - frequently (this usually means that I am also going to have spasms)o back pain – lower back, shoulder blades most severe.o Thinning of hair, and hair losso Temperature regulation irregular –Feel very cold, at room temperature.Psychological Symptomso Euphoric mood, then sad, variable mood swings {not anger}o Panic – induces tremorso Anxiety – Depersonalisation {frequently}, Derealisation {infrequent} - feeling cut off or distant from the immediate surroundings. Possibly the onset of depression or an anxiety disordero Forgetfulness – short term memory losso restlessnesso nervousnesso irritabilityThe only relief I have found from spasms and my walking problems which are complicated by spasms is through medical marijuana use. I also find that clogs help my walking problems when I am not too fatigued.
    lhamo84 2 Replies
    • October 20, 2008
    • 10:17 PM
    • 0
    Flag this Response
  • Has she had her B12 checked? I had about 25 of the symptoms you mentioned and most of them have improved with B12 supplements within 30 days. Also check the Thyroid angle as mentioned above. I always urge people to get a copy of the blood work and tests they have and research themselves. The internet has a lot of information about blood work. Don't take fine at face value. I went to the hospital and got copies of my MRI, Xray, CT scans and all the reports along with a copy of all my lab work. My B12 was 347 and I was having lots of symptoms of pernicious anemia. The doctor told me it was "fine." It took my persistance for him to decide it was worth a look closer look at. He wasn't very pleasant about it either. I also have low neutrophils and elevated monocycte levels. My doctor still doesn't think that is of concern. It is for me though. Good luck I wish her well. Is she on any meds to help her cope? Cymbalta helped me beyond belief to cope between Dr appts and specialists.
    CANDERSON 18 Replies
    • October 21, 2008
    • 01:33 AM
    • 0
    Flag this Response
  • Endocrinology would be to consider, hormonal imbalances can cause a lot of symptoms. Thyroid being one of em, but not the only one. Does she have any issues with her menstrual cycle?
    geenie 39 Replies
    • October 22, 2008
    • 00:15 PM
    • 0
    Flag this Response
  • I have had Thyroid Cancer. Was diagnosed in 2006 and cleared in 2008. I am also going into Radiation Therapy (I will be treating cancer/administering chemotherapy) If the lymphnode causes no pain and is growing slowly then that is a HUGE sign that it could be malignant (Cancerous). I would ask for a full body scan. My Thyroid Cancer had lung mets (spread to my lungs) quickly, and a full body scan would catch any mets and also if there are any tissues in the throat area. A TSH test to see your Thyroid Hormone won't necessarily detect any thyroid cancer (mine didn't). If the full body scan finds malignant tumors of Thyroid Cancer, then a simple Radioactive Iodine pill can be taken after an annoying low-iodine diet of about 2-3 weeks, and your sister can be rescanned and this is a very fast (obviously) and effective way of treating this cancer. My lungs were filled with tumors in 2006, and in 2007 there were only 2 large tumors left. (: Good luck!
    Anonymous 42789 Replies
    • February 20, 2010
    • 06:41 AM
    • 0
    Flag this Response
Thanks! A moderator will review your post and it will be live within the next 24 hours.