Discussions By Condition: I cannot get a diagnosis.

B12 dropping very rapidly, NOT pericious anaemia

Posted In: I cannot get a diagnosis. 2 Replies
  • Posted By: Anonymous
  • March 20, 2009
  • 01:22 PM

Hi all
I have a bit of a mystery with my B12 levels. I do not have pernicious anaemia, but not only can I not increase my B12 levels dietarily, they drop extremely rapidly after injections. A recent example is that a couple of weeks after a course of 3 injections, my level was at about 1400. After just 5 weeks I was down to 250, and feeling ill from it. I have been down to 80 in the past as well (have been deficient on and off for 2 years now). This really rapid drop has happened twice now, and is really affecting my health. I have seen a haematologist who appeared unconcerned, but offered no explanation as my haematocrit (sp?) was normal. My GP is stumped, she has never seen it in 30 years. I am concerned as I have been ill (with undiagnosed celiac) for a long time, I am working really hard to get my health back, but I can't seem to get this under control. If someone with pernicious anaemia can get by on 1 injection every 3 months, why should I need to have them all the time?
Any thoughts would be much appreciated.

Confused and anaemic!

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2 Replies:

  • Hi allI have a bit of a mystery with my B12 levels. I do not have pernicious anaemia, but not only can I not increase my B12 levels dietarily, they drop extremely rapidly after injections. A recent example is that a couple of weeks after a course of 3 injections, my level was at about 1400. After just 5 weeks I was down to 250, and feeling ill from it. I have been down to 80 in the past as well (have been deficient on and off for 2 years now). This really rapid drop has happened twice now, and is really affecting my health. I have seen a haematologist who appeared unconcerned, but offered no explanation as my haematocrit (sp?) was normal. My GP is stumped, she has never seen it in 30 years. I am concerned as I have been ill (with undiagnosed celiac) for a long time, I am working really hard to get my health back, but I can't seem to get this under control. If someone with pernicious anaemia can get by on 1 injection every 3 months, why should I need to have them all the time?Any thoughts would be much appreciated. Confused and anaemic!hello, are you in the U K???????? I have that, and theres no way i can get by on 1 shot a month which was cyanocobalamin b12, it's toxic and an inactive b12, am now using methyl cobalamin lozenges and adenosylcobalamin b12 lozenges, anyone who has below b12 level of 550--500 is considered deficient, you are extremely defiecient. please go to the b12 forum in this website, you'll learn all about it. what kind of testing did your doctor do to rule out pernicous anemia. it's not just a matter of getting your levels up, but also whats getting into the cellular level into the tissues, are you getting hydroxocobalamin injections, how often, thats just one step above the kind i was getting, in the since that its not toxic, but it to is inactive b12, it is amazing how dumb doctors are in this subject, you need help fast, so go to b12 deficiency commonly misdiagnosed , tell us your medical story forum, the people there know what they are talking about.
    sickinva 87 Replies Flag this Response
  • Have you had your GP test for parasites? Hook worm found in the intestines can cause rapid depletion of b12. This has happened to a friend of mine who went through test after test after test until they finally did a simple stool sample! Good Luck!
    Anonymous 42789 Replies Flag this Response
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