Discussions By Condition: I cannot get a diagnosis.

B-12 Deficiency or worse?

Posted In: I cannot get a diagnosis. 7 Replies
  • Posted By: Michael229
  • February 21, 2008
  • 02:51 PM

I would like some advice with my blood results. I recently have had tingling in my hands and feet.
My FBC came back with the following abnormal results...
Lymphocytes = 1.1 (range is 1.4-4.0)
Mean Cell Haemoglobin = 33.6 (range is 32.0)
My B12 was 218.0 (range is 179.0 - 1162.0)
I have two questions. Although my B12 is in normal ranges could it still explain my tingling.. Is it low enough? Secondly, could low B-12 cause lower levels of Lymphocytes?

I am terrifed about my Lymphocytes. Is this worryingly low or could it just be a minor problem. I noticed that my white blood cell count had also gone down a bit


Michael

Reply Flag this Discussion

7 Replies:

  • I would like some advice with my blood results. I recently have had tingling in my hands and feet.My FBC came back with the following abnormal results...Lymphocytes = 1.1 (range is 1.4-4.0)Mean Cell Haemoglobin = 33.6 (range is 32.0)My B12 was 218.0 (range is 179.0 - 1162.0)I have two questions. Although my B12 is in normal ranges could it still explain my tingling.. Is it low enough? Secondly, could low B-12 cause lower levels of Lymphocytes? I am terrifed about my Lymphocytes. Is this worryingly low or could it just be a minor problem. I noticed that my white blood cell count had also gone down a bitMichael Are you on any medications currently? Best wishes DOM
    acuann 3080 Replies
    • February 21, 2008
    • 02:54 PM
    • 0
    Flag this Response
  • No I am on no medication.. I forgot to mention that my lymphocytes were 1.3 six weeks ago.. Also I had a blood test four years before and they were 1.4
    Michael229 22 Replies
    • February 21, 2008
    • 02:58 PM
    • 0
    Flag this Response
  • B 12 deficiency would tend to make you anemic, meaning low hemoglobin and hematocrit. You red blood cells would tend to be big, or macrocytic (meaning a higher MCV). Also, your neutrophils would have extra lobes in their nuclei, although this likely would not be picked up by an automated machine...You typically have a couple of months of B12 stored in your liver.I think your doctors should be looking for other reasons for the numbness and tingling. In the mean time, if you're still worried about your B 12, they make little lozenges to put under your tongue.Best Wishes
    Anonymous 42789 Replies
    • February 21, 2008
    • 10:17 PM
    • 0
    Flag this Response
  • I would like some advice with my blood results. I recently have had tingling in my hands and feet.My FBC came back with the following abnormal results...Lymphocytes = 1.1 (range is 1.4-4.0)Mean Cell Haemoglobin = 33.6 (range is 32.0)My B12 was 218.0 (range is 179.0 - 1162.0)I have two questions. Although my B12 is in normal ranges could it still explain my tingling.. Is it low enough? Secondly, could low B-12 cause lower levels of Lymphocytes? I am terrifed about my Lymphocytes. Is this worryingly low or could it just be a minor problem. I noticed that my white blood cell count had also gone down a bit MichaelActually yes, your B12 value is too low and can cause nerve damage. The "normal" range cited is not well chosen. In Japan they want to see 1000.Just take 2000 micrograms of B12 daily by mouth and you should get improvement after 2 months. (It will take a while and may get a little worse before getting better). You can buy Solaray or other B12 lozenges in health food stores. There is no danger of overdose. You need that large a dose because you have impaired absorption.It worked for me. I am not a physician.Don Bradydbrady@pobox.com
    Anonymous 42789 Replies
    • August 21, 2008
    • 10:24 PM
    • 0
    Flag this Response
  • Actually yes, your B12 value is too low and can cause nerve damage. The "normal" range cited is not well chosen. In Japan they want to see 1000. Just take 2000 micrograms of B12 daily by mouth and you should get improvement after 2 months. (It will take a while and may get a little worse before getting better). You can buy Solaray or other B12 lozenges in health food stores. There is no danger of overdose. You need that large a dose because you have impaired absorption. It worked for me. I am not a physician. Don Brady dbrady@pobox.com Yes, after researching this more I absolutely agree you B12 levels are low. Serum blood B12 tests are not very accurate. Since you have B12 deficiency symptoms, I recommend both injections and sublingual lozenges: JUST MAKE SURE YOU TAKE METHYLCOBALAMIN B12, not cyanocobalamin, which is toxic. Jarrow's Methyl B12 is the best rated lozenge. Get on the B12 misdiagnosis thread and start reading thru the copius pages. Very informative. Best wishesDOM
    acuann 3080 Replies
    • August 22, 2008
    • 00:38 AM
    • 0
    Flag this Response
  • Dear Michael, Im currently in nursing school I stumbled across your post randomly looking for the range values for B-12, I have actually worked with a Doctor who has done extensive research on B-12 deficiency, it stems usually from an insufficiant secretion of intrinsic factor your body normally get the b-12 it needs from the food's you eat, absorbs it in the illium of your small intestine then stores quite a large amount in your liver. It can take months for your body to become depleted so a low level does give some room for concern, some drugs can also interfere with the absorbtion of b-12 such as ascorbic acid(Vitamin C but im NOT saying to stop eating healthy things with vit c in them just that it is possible), cholestyramine, colchicine, neomycin, cimetidine, and hormonal contriceptives. your going to want to have your doctor do a CBC and Blood smear to check the sizes of your red blood cells, test for folic acid and b-12, get a gastric analysis to measure the volume and acidity of gastric juices, and most importantly a *******SCHILLING TEST******** this test specifically for the uptake of b-12 and to see if your body is absorbing it correctly.about your Lymphocytes, i have not found anything in my research that states a corrilation between Lymphocytes and b-12(b-12 is necessary for normal DNA synthysis in RBC not in white)each facility has different policies on what the range is for lab values and can very from one facility to the next. to evaluate your lab result much more information would be needed only because lymphocytes are a part of the bodies immune system so the low count could possibly be caused from an outside source such as a virus or bacterial infection or even your body itself, since this seems to be worrying you my advice would be to do some research and find a doctor who specializes in hematology. but it would be best to nip it in the bud and dont forget your the patient you have a voice dont be afraid to voice your concerns to your doctor or the nurse that is taking care of you. and dont forget to be positive :) a positive outlook can do wonders for the body. these are just mearly suggestions and in no way a medical diagnosis. you would have to visit your doctor or another doctor to properly determine the course of action.I hope this helped, best of luck!-Marlayna
    Anonymous 42789 Replies
    • September 14, 2010
    • 02:17 AM
    • 0
    Flag this Response
  • For some that level is low enough to cause symptoms. MANY get tingly hands and feet at that level. (there is a HUGE vitamin B12 thread at this site where many who had blood test results within normal range, turned out it was B12 deficiency causing their symptoms). I myself thou i have normal range B12 results at 337, ended up finding that B12 injections helped me some, without them, i couldnt function.. had SEVERE memory issues and brain fog and other symptoms. Before B12, i was forgetting things like how to make toast and how to put petrol into my car! One can also not show up deficiency on a blood test but still be very low in ones actual body tissues. (there has been at least one study done showing this)
    taniaaust1 2267 Replies
    • September 14, 2010
    • 04:03 PM
    • 0
    Flag this Response
Thanks! A moderator will review your post and it will be live within the next 24 hours.