Discussions By Condition: Gastrointestinal conditions

Severe postprandial abdominal pain, any ideas?

Posted In: Gastrointestinal conditions 2 Replies
  • Posted By: VPrice1030
  • July 18, 2013
  • 03:20 PM

Hi all, thanks in advance for any help. I'm a 28 y.o. female with no other medical history except for renal obstruction repaired surgically at age two.

Starting about six months ago, I started developing early satiety and postprandial abdominal fullness and pain. I also had extreme fatigue and night sweats. I have gone from doctor to doctor (rheumatologist, GI specialist, neurologist) and none had any idea. I've finally found a good PC who is looking at the whole picture, but at this point, she is stumped. Here are my symptoms/lab work:

-Postprandial abdominal pressure
-Generalized upper (vaguely right quadrant) abdominal pain and tenderness
-Orthostatic hypotension
-Salt Cravings
-Night sweats
-Fever or low body temp (Sometimes I'm at 95.4, sometimes I'm at 101...usually running a fever at night)
-Extreme fatigue
-Headaches
-Nausea and vomiting 60-90 minutes after eating
-20 lb weight loss (I'm quite thin to begin with, my BMI is now at about 18)
-Muscle weakness, loss of muscle tone
-Nighttime lower back pain
-Hot, flushed skin
-Generalized itchiness

Labs have shown the following:
-TSH of 9.2 (TSH taken about two months ago was well within the normal range)
-Morning cortisol of 32.4
-Normal brain MRI
-Abdominal CT showing what looks like slow/lack of bowel movement (I don't remember the term... I don't feel constipated and am having normal BM's, but the CT and x-ray showed otherwise... the doctor said they didn't look normal, but in a way she couldn't put a finger on), as well as slight ureteral stenosis on left kidney (the one I had surgery on)

-Biopsy of abnormally large/shaped lymph node was benign
-Erratic blood glucose levels, high two-hour glucose level
-No celiac disease
-Normal PTH and T4
-RF Negative
-Severe vitamin B and D deficiency, not remedied by OTC vitamins
--Slight anemia
-low RDW
-low EO# and MONO#
-Elevated HS-CRP
-Elevated LDH
-Urinalysis normal

-Currently waiting for results of ACTH stimulation test
-Normal upper endoscopy about two years ago

My doctor was convinced it was Addison's, but the extremely high morning cortisol obviously doesn't fit that, and I have zero symptoms of Cushing's. I had read about Chronic Mesenteric Ischemia (not spelled right, I know), and it vaguely seems to maybe fit, but I'm at a loss.
Does anyone else have any ideas? I'm starting to lose my mind, I can barely function day-to-day and waiting days/weeks for tests and to see specialists is killing me.

Thank you again :(

Reply Flag this Discussion

2 Replies:

  • If you have severe Vitamin B12 deficiency, this can cause many problems. In particular, B12 deficiency has been linked with muscle weakness, tingling in fingers and toes, depression, anxiety, weight loss. If you have GI problems, this can make it very difficult for you to process vitamins through your digestive tract hence you may need to have B12 injections. You may want to ask your doctor to also run tests to check your MMA levels. If this is high, it is a sign that you are not able to process vitamin B12 via your stomach. This should start right away to prevent any further damage from occurring due to the B12 deficiency. People have ended up unable to walk and confined to wheel chairs because their doctors failed to diagnose and treat this very treatable disease. In addition, Vitamin D can also cause similar problems with muscle aches and pains, fatigue, etc. That needs to be treated right away, too. The doctor should have you on at least 2,000 iu of vitamin D a day. I had a vitamin d level of 12 which is very low and after over a year of being on 2,000 iu a day, I'm only up to 42 which is well below where you need to be ideally. I would also have your doctor run a test called ANA, antinuclear antibody to see if you have some sort of autoimmune disease. Low vitamin d and vitamin b12 are also associated with autoimmune issues.
    Anonymous 42789 Replies Flag this Response
  • there could be some big problem, before it results in some other suffering and pain consult a weight loss surgeon because getting pain in abdominal is very risky .
    shreya 15 Replies
    • August 12, 2013
    • 10:10 AM
    • 0
    Flag this Response
Thanks! A moderator will review your post and it will be live within the next 24 hours.