Discussions By Condition: Cancer

AML relapse after BMT

Posted In: Cancer 12 Replies
  • Posted By: tatesmom
  • January 9, 2007
  • 04:18 AM

I have a 12 yr old daughter who was diagnosed with AML in 03/06...she went through 2 rounds of chemo without going into complete remission...she then underwent a BMT with my 10 yr old son being the donor...he was a perfect match...she relapsed on 12/27/06..with 60% in blood and 90% in bone marrow....she just completed a 5 day round of chemo with a new drug called clolar....we don't know if she is in remission or not....the docs said that since she relapsed after BMT...then her prognosis for long term survival is very poor....they said that they could get her into remission probably, but were not going to be able to keep her from relapsing again....does anybody have any suggestions as to what we need to do as far as further treatment...i.e., where to take her, hospital referrals, etc......

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  • Hi Tatesmom, My sis just finished round down at MD Anderson in Houston for Hodgkins. Had stem cell transplant and is in remission. They seem to know what they are doing. Hope this helps and keep on looking. Bob
    panhandle 5 Replies
    • January 22, 2007
    • 06:19 PM
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  • My 8 year old niece was diagnosed with AML Nov. '05, received a BMT (brother was perfect match donor) in May '06. She just relapsed this week Jan 23 2007. They plan to get her a second transplant. She has been treated at CHOP - Childrens Hospital of Pennsylvania. That is the number one childrens hospital in the country with the leading AML experts. That is where your daughter should be. If I can be of any help to you - post a message to my niece's carepage at:www.carepages.comlook up patient name - MiaJulietteor email me at bridgetmc@hotmail.combest wishes to your daughter.sincerely,bridget
    Anonymous 42789 Replies
    • January 30, 2007
    • 03:48 AM
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  • We are concerned that our daughter (dx AML 3/20/06 BMT 10/5/06 perfect sibling match) may be relapsing. Re: Pallor it seems, decrease in energy, slight increase in some of her sub labs and fainting. All these were her early symptoms prediagnosis. Can anyone tell me what they saw in the labs that indicated relapse. Thank you,Debora
    Anonymous 42789 Replies
    • February 21, 2007
    • 04:14 PM
    • 0
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  • I have a 12 yr old daughter who was diagnosed with AML in 03/06...she went through 2 rounds of chemo without going into complete remission...she then underwent a BMT with my 10 yr old son being the donor...he was a perfect match...she relapsed on 12/27/06..with 60% in blood and 90% in bone marrow....she just completed a 5 day round of chemo with a new drug called clolar....we don't know if she is in remission or not....the docs said that since she relapsed after BMT...then her prognosis for long term survival is very poor....they said that they could get her into remission probably, but were not going to be able to keep her from relapsing again....does anybody have any suggestions as to what we need to do as far as further treatment...i.e., where to take her, hospital referrals, etc......How is she now? Did they get her into remission? My 15 yr old daughter was diagnosed 5/2006, got a bone marrow transplant 10/2006 and relapsed 3/2007. They will try another BMT with her sister (we had 2 perfect matches in the family) I'm curious to see outcomes and options...
    Anonymous 42789 Replies Flag this Response
  • We have heard about Mylotar being a smart chemo that only goes after cancer cells for AML relapse.
    Anonymous 42789 Replies Flag this Response
  • Tatesmom, have you considered Memorial Sloan Kettering? It's widely considered to be one of the best cancer centers in the world, if not THE best. The doctors there are extremely knowledgable and friendly, and treat you like a human being, not as some kind of lab experiment.Just remember, and tell your daughter this as well- NOTHING is impossible. Just because the indications aren't good doesn't mean she won't recover and live a happy and healthy life. There are always stories of "X months to live" or "next to impossible" with the person beating the odds and baffling the doctors.
    Anonymous 42789 Replies Flag this Response
  • Duke University Med Center in Durham NC is the pioneer hosp for cord blood transplants. The treatment is the same only stem cells from a new born's umbilical cord and placenta are used. I just went through their protocol and am on day 80 something post transplant for AML.Cord blood has been shown to have a higher cure rate, but is slightly more dangerous bc blood counts are down for a lil longer than a reg allo or auto transplant. The doc is right, it will be very diff to get her in remission and probably impossible to get her to stay there at this point. I cant spell the chemo drug name either, but it was used in my treatment twice before the transplant and that drug is much rougher than the other chemos I had been treated with (the choloro whatever, it is still in clinical trials).For my transplant fludarabine and radiation was used, and honestly this was the easiest treatment I have had. Unfortunatly if she is not responding treatment this maybe a time for her to consider quality vs longevity. I know that is a very hard thing to hear, but is true. Only she can make this decision. Dont force her into treatments she doesnt want, especially on behalf of your own fears. i know it will be difficult to watch this process, but...
    Anonymous 42789 Replies
    • October 13, 2007
    • 03:15 PM
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  • I have a 26 year old daughter who was diagnoised with AML in Aug of 2005 and has no chance of a BMT because of a botched surgery which caused her to lose her lung and gave her heart problems. She has 2 lovely childern 2 yrs and 5 yrs. any one have any ideas on clinical trials anything please she has relapsed and has given up.... respond to this message board. PLEASE!!! HELP!!!!
    Anonymous 42789 Replies
    • January 22, 2008
    • 05:52 AM
    • 0
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  • Hello my 11yrs old son has aml started his treatment on 9th feb2007 has 5 set of chemo afeter 3 mts he replase had 4sets more of chemo and a perfect match and did his bone marrow transplant after 4mts replase again now has just finish 2 more rounds of chemo and replase again and they have stop all treatment we have visited CHOP and they said the same thing they r unable to help pls we r very desprate if anyone has anyidea of where else we can go pls send me some info .Thank you
    Anonymous 42789 Replies
    • September 29, 2008
    • 00:28 AM
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  • How is she now? Did they get her into remission? My 15 yr old daughter was diagnosed 5/2006, got a bone marrow transplant 10/2006 and relapsed 3/2007. They will try another BMT with her sister (we had 2 perfect matches in the family) I'm curious to see outcomes and options...My father has AML and is being treated by MD Anderson. There is no where better in the US. They have teams that ONLY work on AML patients. My dad has a team that works on his specific type of AML - FLT3. I have never seen a cleaner hospital all the staff always wear gloves and smocks and masks. Even the staff that brings food takes precautions. they bring you ice in sterile bags. Lots of clinical trials there. They tell my dad they he is probably going to make it to a transplant while the staff at our local hospital tells us they can only make him comfortable for the short time he has. They are leaps ahead in dealing with AML. Good luck to you and your daughter.
    Anonymous 42789 Replies Flag this Response
  • I have a 26 year old daughter who was diagnoised with AML in Aug of 2005 and has no chance of a BMT because of a botched surgery which caused her to lose her lung and gave her heart problems. She has 2 lovely childern 2 yrs and 5 yrs. any one have any ideas on clinical trials anything please she has relapsed and has given up.... respond to this message board. PLEASE!!! HELP!!!! My 24 year old brother with AML took the option of going for trial therapy with Oxi4503. He passed away the same day of taking this medicine and a very painful death.
    Anonymous 42789 Replies Flag this Response
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  • Screw conventional methods, my mom beat luekemia and i beat hodgkins using natural products....they gave my mom six months to live and said she'd never be cured unless she had a bone marrow transplant. She never did and she has 0% cancer left. That was eleven years ago. They told me mine couldnt be cured that way....I quit chemo way before they wanted me too, it was killing me but I was taking a natural product and I beat Hodgkins in less than four months. My tumor was the size of a pineapple and I just got a one year check up and everything is great-not likely that a relapse will happen. Its hard not to believe in this product when I have witnessed first hand what it can do for people.
    janeld 2 Replies
    • August 27, 2011
    • 07:51 PM
    • 0
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